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ҽҩȫ > ҩ > ҩ > A > Ҷ

Ҷ

2018-01-21 10:12 Ķ:

ȫвҩࡷҶ

ҩơҶ

ƴài Yè

ӢFOLIUM ARTEMISIAE ARGYI

Ұ

ԴƷΪտֲArtemisia argyi Levl. et Vant. Ҷļδʱժȥʣɹɡ

״Ʒ飬ж̱ҶƬչƽ״ԲΣ״ѣƬԲ״ΣԵвĴ־ݣϱɫɫϡëٵ㣻±Ұɫë㣬ζࡣ

𡿱Ʒĩ̺ɫë֣һΪëϸ۲ȳ24ϸһΪԷë35ϸϸسŤ䡣ëЬΣ 46 ϸԵ϶ɣޱƴؾֱ37μm,ҶϸС

ơװ̿Ҷ̿:ȡҶڹڳ󲿷ֳɽɫ״ףȺȡɸҲˮǣȡɣֹȼÿ100kgҶô15kg

ζ࣬£С

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2ڷҶƼԼСʱж֢״ɿڿʣθʣģŻ£̶ȫͷζ֫Σϵͳ߶˷𣩣ηȫڻȱ̱񾭷估Ѫܱ𣬿ӹѪѪиϸлϰжԻ͸סҪϵͳȬೣнþȺ֢жиоʧ롢סε֢״֡

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Ҷ

ҩǵ䡷Ҷ

ҩơҶ

ƴài Yè

ʫ̨ɡšעҽݣ¼IJݣšޭޭƲݣĿҰҽҪ𰬣ԭβӡ㰬Ұͷ

ݾע

ԴΪտֲҶĶδҶïʢʱժɹɻɡ

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ڡĿ"ðҶó¾ߣϸν֮찬Ļ˼ȡҶȥмʯľƵ죬ȥңȡٵΪȣʱĻ븾ɢ찬ôɵɱӣٵΪĩãŴƳ߽ԲѡϡիʡƣƬͬ룬ʱϸĩһҲ"

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١¼"ζ࣬΢£޶"

ڡƱݡ"ȡ"

ۡĿ"£ȡ"

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ۡ¡"ġ"

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ƢθʹװĩǮ׼򷽡

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ʪҶ̿ݷưصȷ֡ϸĩ͵࣬󡣣ɹšвҩҽƷѡࡷ

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עֲĹʵʵ๩ҩãר

ֲͬҰ𰬡°45100סвҶ12״ѣƬԲΡΣȫԵоݣҶٵ㣬ͺ汻ɫ˿״ëϲҶޱƬխ.910¡ȫ󲿷ֵзֲҶҶá

ժ¼ҩǵ䡷


лݡҶ

ҩơҶ

ƴài Yè

ӢArgy Wormwood Leaf, Ai Ye, Aiye, Argyi Leaf, Chinese mugwort leaf, Folium Artemisiae Argyi ArtemesiaARTEMISIA ARGYIArtemisia leafArtemisiae Argyi FoliumChinese mugwort leafdried leaf of artemisi

1.ݾע

2.ҽ¼ҶҰ²ɣ壬硣

3.ͼҶɲҰ񴦴֮ԸΪѡƴ־İٲʤ磬ҶףΪѡҶɣ¾÷á

4.ĿҶݡҰʱΪѣͼΣΩν֮ν֮Գ

ԴҩĻԴΪտֲﰬҶ

ֲﶯArtemisia argyi Levl .et Vant. [A. argyi Levl. Et Vant. Var .incana Pamp.]

պʹأ9£26»δʱȡϲ֣ժȡҶƬңɹɡ

ԭ̬ ݱ50-120cmȫܱɫëвϻϲпչбĻ֦Ҷ²ҶڻڿήвҶ״λԲΣ6-9cm4-8cmɶ̻ԳıҶ״ҶƬ״dzѣƬԼ2ԣШΣƬֳƬԵгݣ汻˿״ëаɫܻٵ㣬汻ɫɫëϲҶСѻ򲻷ѣޱͷ״гɸ״Լ3mmֱ2-3mm㣻ܰƬΣܰƬ4-5㣬ԵĤʣ汻ëɫԣڲԡݹ1mmë7-10¡

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Դֲֲȫ󲿷ֵ

ࡿѧ ϲůʪͺɷֳ֡ʵΪˡ

༼ ÷귱ֳ3-4ھԣ֣33cm×33cmѨÿѨ3-4꣬ѹʵˮ

ÿиݣʩ2-3ΣɽջУһ579£ʩΪ3-4Ҫ֡

״״ Ҷ飬ж̱ҶƬչƽ״ԲΣ״ѣƬԲ״ΣԵв־ݣϱɫɫϡëٵ㣬±Ұɫë㣬ζࡣ

ҶɫࡢҰɫëࡢŨΪѡ

΢ ĩ̺ɫٷë֣һΪTëϸڲȳ2-4ϸһΪԷë3-5ϸϸسŤ䡣ë۳ЬΣ46ϸԵ϶ɣޱ۲ƴؾֱ3-7μmҶϸС

ѧɷ֡1.Ҷӷ0.45%-1.00%м2-׻2-methylbutanol2-ϩȩ2-hexenal˳ʽ-3-ϩ-1-cis-3-hexene-1-olϩTCMLIBicycleneα-ϩα-thujeneα-ϩα-pinene,ϩcampheneϩsabineneβ-ϩβ-pinene1-ϩ-3-1-octen-3-ol248--϶ϩ[248-pinthadiene]-ɡأp-cymene18-Ҷ18-cineoleγ-ϩγ-terpineneartemisia alcoholαϩα-terpinene,׻պϩdimethylstyreneԣcamphorԣborneolԣdioborneol4-ϩterpinen-4-ol-ɡ-α-p-cymen-α-olα-ʹα-ter-pineol˳ʽɴcis-pieritolϩͪverbenoneҽﴼmyrtenolʽ곱ɴTCMLIBans-piperitolʽέTCMLIBans-carveol˳ʽ-έcis-carveol-˳ʽ-3-ϩcis-3-hexenyl acetet-ȩp-isopropyl-benzaldehydeͪcarvoneέϩͪcarvenoneȩperillaldehydebornyl acetateմperilla-al-cohol㾣ӣcarvacrolͷӣeugenolţͣϩcopaeneβ-ϩβ-borboneneβ-ϩβ-elemene׻ͷӣmethyleugenolʽ-ϩTCMLIBans-caryophylleneβ-ϻϩcis-β-farneseneȄϩhumuleneβ-ϩβ-maalieneʽ-β-ϻϩTCMLIBans-β-farnesceneβ-ϩβ-selineneγ-ϩγ-muuroleneγ-ϩγ-elemeneα-ϩα-muuroleneȻneryl propionateξ-ϩξ-cadineneϩcaryophylleneoxide԰ȴledolʮȩpentadecanalϻϩͪhexehydroarnesylacetone-dibutylphthalateᣨpalmitic acid60ֳɷ[1]ݱɽɽҰҶĻӷУд34ֳɷ֣кϸߵģϩlimoneneϩα-β-ϩ˳ʽ-β-ϻϩα-ˮϩα-phellan-drene18-Ҷأα-ϩϩisopentylcy-clohexeneԣ4-ϩ˳ʽ-ɴcis-piperitoléciTCMLIBonellolα-ϻϩ-4--4-oct-7-en-4-ol׻methylisopropyl benzene18-Ҷأˮϩcamphene hydrate14-Ҷأ14-cineoleԣԣ4-ϩα-ʹʽ-έͪȩͷӣα-ϻϩ԰ȴ2-N-13-컷2-N-propyl-1,3-dioxolaneα-ˮϩᣬ2-ૼ״2-hydroxy methyl teTCMLIBahydropyranŸͪeucarvone˳ʽɴͪartemisia ketoneͪpiperitoneͪisopipe-ritenone޲ϩͪ266-׻-24ϩͪ266-TCMLIBimethyl-2,4-cycloheptadien-1-oneα-ϩα-curcumene⨺dihydroacinidiolideëϩwiddrene22-׻-3-ϩvinyl2,2-dimethyl-3-henyl-propi-onate32ɷ[3]Ҷͪɷ֣57-ǻ-634-ͪeupatilin5-ǻ-6734-ļͪ5-hydroxy-6,7,3,4-teTCMLIBamethoxyfloxyflavone[4]ɷ֣ɼcryptomeridiol[56]yomogin[57]1--4β-Ҷ-21113-ϩ-128β-[1-oxo-4β-acetoxyeudesma-2,11(13)-dien-12,8β-olide]1--4α-ҴҶ-21113-ϩ-128β-[1-oxo-4α-acetoxyeudesam-2,1113-dien-12-8β-olide][5]ɷ֣α-β-֬amyrinƣfriedelin[5]α-β-֬Ҵamyrin acetateϩͪlupenoneճùϩͪgluctinoneϩͪfernenone24-Ǽ׻ľͪ24-methylenecycloartanone׶ž鴼simiarenol3β--9β19--23Eϩ-2526-[3β-methoxy-9β19-cycolanost-23-25,26-diol]ɷ֣β-޴β-sitosterol޴stigmasterol[5]ethyl palmitateethyl oleateethyl linoleateʽıǼ׻ᣨphenylitaconic acid[8]Լܡͭп̡ơþԪ[9]

ҩá1.ã1.1.Ҷ̿Ҹ˾α-ѪB-Ѫ׺˾ٰ׺˾˫ɫɫɫݲݸ˾10ָпáҶ4×10-3ŨȣԹܷԷ˫ɫɫ󳦸˾˺˾˺˾˾־áҰҶѬѼۻƻۻơƵȻأԽɫѪ󳦸˾θ˾׺˾˺˺˾ŧ˾ݲݸ˾˾Լ˸˾H37RVɱáѬܼ˴ϸ˾ƺ󣬼չᣬԲ̺ڸԣ⻹ǿ״ƤϸɷӦǿij̶Ȳ綯ʱţ״ƤϵϸɻĽ˲һµģΡƢܵʱɻܼ½

1.2.СҰҶѬڶ²Ҳ־áСҰˮԹڶԶ²Ҳһá

1.3.ҰˮԹڶԽɫα-Ѫ˫׺˾˾˺˺˾һȾв̶ͬȵá

2.ãҶҺƤѢ־Ϊ΢˵ȼҺȽϣ15%ŨʱɫëѢʼƣ30%Ũʱ״ƤѢëѢɫȻ⣬ΪϻѢϻѢɹű֡ɽѿѢͬëѢɫëѢɫëѢɫëѢȾֹͣܺҵ֤Ҷˮ14ԹڶɫëѢϻѢ¶ŰСѿѢë״СѿѢɫƤѢūϾƤв̶ͬȵáͬʱѸֲⶨҶѬϻѢϻѢɹű֡ͬëѢɫëѢɫëѢ״ƤѢɫСѿѢëѢֺëѢСѿѢʯëѢϰ˿ĸ²Ƥв̶ͬȵԿá

3.ƽã3.1.ҶֱɳƽҲܶԿȻ֯󣻲ιҶ0.5ml/kgθ-鰷Һ´ãҶ2×10-4ml/kgɳãܶԿȻҶͼ-80ƳɵĻҺƷ֯ͷӦʣSRS-Aֱ׿ӦʵãƷ֯ƽͷӦʣ԰Ҷһιθ󣬷֯ӦʺͲԡ1981˴ӰҶƽýǿзезõƽýǿĵ壬α-Ʒϩͷʽ-έʵƽñȰҶǿҶзõƷϩ-4240-300mg/kgθҩα-Ʒϩ80-120mg/kgθܶԿ鰷ɷַʽέTCMLIBanscarveolβ-ʯϩβ-caryophylleneҲʾƽá1%α-Ʒϩ룬鰷,ɶԿѰ׵λеܵĸı䡣

3.2.Ұ֧á

4.ãȡҶͽң2%ҶɻҺÿ1mlҶ75μl0.8ml/100g0.3ml/100gʮָעҩֱΪҶһͶ顣Զȥ⵨ᣨDHCÿƬ0.25g20%Һ0.3ml/100gʮ֬ҩȻ̼ж飺Ȼ̼1mlkgθ1Σж24Сʱʵ飬ðҶ0.3ml/100gʮָҩ2%0.3ml100gʮָҩС3飬Ҷ飬0.2ml/10gʮָҩȥ⵨飬5%ȥ⵨0.2ml10gʮָҩˮ飬0.2ml/10gʮָҩʵҶͻҺ0.8ml/100gʹ֭91.5%ҩǰȽмԲ죻0.3ml100gʹ֭89%ҩǰȽмԲ죻ȥ⵨ʹ֭83.2%Ȼ̼ж֭Ҳӣȣüάʱ̣2%¶Ե֭Ӱ졣ҶͶСҲԵãʹ䵨֭26%

5.ѪСۼãҶβ-޴57--63'4'-ͪǶѪСۼá˵о˰ҶƷͬصİҶЧɷֶѪСۼʵӰ죬ҶIJͬƷѪСۼʵø졣ƷʵӰܴ󣬲ͬƲƷʵкܴ𡣳̿׳Чϲ׳̿ҶѪСۼкǿã3ˮƽ϶ܼԵѪСۼp<0.001ҶֲܼͬȡУԴѪСۼΪͻܼȷ£ȡҲãЧá3ֲͬصİҶˮܲλѪСۼãp<0.001ЧְҶ136mg/mlʱ3ְҶIJ첻ԡӰҶȡֳɷ֣β-޴57-ǻ-63'4'-ͪѪСۼмŵáȻЧɷȣβ-޴0.71.35mg/mlʱԵںߣp<0.001

6.ֹѪãҶˮҺùθдٽѪҺãΪҶֹѪδ֤ʵҶΪٴϳֹѪҩ¾ֹѪ̿ãҩʵ֤Ҷֹ̿ѪǿѧȶֹѪý˱ȽоʵɼƷ2-5̿Ʒ100%ˮҺʵСѪѪʱ䣬ˮȽϣԲ죬ԺƷ2180桢10ӣƷ3180桢20ӣͺƷ4200桢10ӣֹѪΪԣƷȽҲԲ졣ƷֹѪá鰬Ҷ̿ɸú淨1810-20Ӽ20010ӣƷɫΪѡ

7.θӹãҰ˷ܼӹǿֱƽӹ˷áСҰˮҺóڴʱá

8.ѪϵͳãСҰˮҺڴʱáӿǵİArtemisiatauricaTauremizinһֱϩġèĺλèľǿèIJܼʣʹѪӣصá

9.ãҶ0.5mlkgθѰ׵ݿжԿãɽʡ

10.ãα氬ҶҪ京ʣʹ´̷ȵļõ½üѽʲΪҩʹáСͿͶ֢ģͣðҶӷ͸СƤעע0.0125gпЧЧΪ57.8%75.O%pֵС0.001Ҷӳͱ˯ʱ䡣СҰˮҺöѪܹʱӰ죬СǻעɽëϸѪͨ͸ԣLochettϷڷãеȣٴ

ԡԣҶСθLD50Ϊ2.47ml/kgǻעΪ1.12ml/kgҶӷͶƤȴ̼ãȳ죬ڷܴ̼θڣڷɰҶ3-5gʳθ֢Ż£պϵͳ˷ܣʼ𺦵ȡ񾭷Եı仯ԼѪܱڱ𣬿ӹѪѪʱ

ơ1.Ҷȥʣȥɸȥм

2.ޣȡɹɾҶޣȥӲҶɸȥм

3.̿ȡҶù߳ɱɫôȺ˿ɸδ͸سȡֹȼպ档ÿҶ100ô154.塷ɵɸȥңȡףʯƣΪưļá׷ɵΪĩʳҩ

5.ĿðҶó¾ߣϸν֮찬Ļ˼ȡҶȥмʯľƵ죬ȥңȡٵΪȣʱĻθɢ찬ôɵɱӣٵΪĩãŴƳ߽ԲѡϡիʡƣƬͬ룬ʱϸĩһҲ

ζζࣻ

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Ρ¾ֹѪɢֹʹʪֹѪѪѪѪѪ©Ѫ¾ʹ̥ĸʹйкת£ʪѢ̴Ӹ

÷ڷ3-10g衢ɢ֭ãĻƳɰѬģ󣻻ˮѬϴ١

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