永利游戏娱乐- 【真人平台】

¼| ע| վͼ
ӭҽҩȫ
| ||
ƫ ʳ ̵
||
ҽҩȫ > ҩ > ҩ > A > κ

κ

2018-01-22 11:14 : Ķ:

йҩ䡷κ

ҩơκ

κͼƬκκ

ƴ Wèi

ӢRESINA FERULAE

κϸҶκ

ԴƷΪɡοֲ½κ Ferula sinkiangensis K. M. Shen κFerula fukanensis K. M. Shen ֬ĩijʢڣִɾϲбռ״֬ɡ

״ƷΪĿ״֬״ɫdzһɫػɫ״ᡢʵп϶ɫdzúɫ֬״ҰɫǿҶ־õζ֮ոС

𡿣1 ȡƷʹܽ⣬ԻɫɫٵμӰҺʹʼԣƣ365nm ¹۲죬ɫӫ⡣

2 ȡƷ0.5ml,УԵɫϺɫټӼ䱽ɫdzУΪϺɫ

3 ȡƷ״жϣϵμ1ΣɲɫΪɫ

4 ȡƷ0.2g10ml̶ԹУˮҴ̶ȣò飬30ӣ˹ȡҺ0.2ml,50mlƿУˮҴ̶ȣҡȡշֹȷ¼Aⶨ323nmͲӦա

ⶨȡƷ 510g ջӷͲⶨ¼ Dⶨ

ƷӷͲ10.0

ζࡢ¡

龭Ƣθ

ΡɢƦɱ档ʳͣѪ֢Ʀ飬ʹ

÷11.5gɢøҩ

ע⡿иá

ءܱգﴦ

ժ¼йҩ䡷

 

ҩǵ䡷κ

ҩơκ

ƴ Wèi

ѬƱݡκȥҩסݡݣޡࣨĿκҩ־κ½вҩֲᡷ

Ʊݡ

ԴΪɡοֲκ½κκ֬ δǰա¶׸ͷжϣҺԶҶIǣԼ10Һ֬ɹ¡ٽ϶ȥһСΡϷգÿ10һΣݽΪֹԼ3¡ﴦܱձ棬ȡ

ԭ̬
ٰκ

ݱǿʱֻȷиҶ5ʼ黨׳ߴ2ףơҶʣ䣻ҶΪ34״Ҷ50ףҶƬλԲΣɫ泣ëϲҶ12ءԻԣɡλ뻨ɡ2030֦ÿ֦Сɡ֦Ի뵥Իɵ򣬻Ի1ƻԻɫ5΢ݣ55ڻꣻ2Ƥϲƽ룬ԻۻԻƣƤ鲻ƻɫλʴ2Ƥӷλë2ң1˫⣬ΡλΣë10ߣɫ3¡4¡5ֲή

ڶɳشֲϸǵʡ

½κ

ݱ50200סҶгҶ34״ҶСҶƬ״ѡɡλ򣬻ɫСܡ˫ԲΡ

ڸ̲ɽϡֲ½

ۿҶκ

ݱߴ2סҶΪ3״ҶСҶλԲΣΪɫӷӹ⻬

ֲ½

״κƷ۶ɴСȵĿ״ɫɫվãΪɫµΪɫdzɫɫͨΪ"ʰκ"

½κ֬ΪҰɫdzػɫ֬״Ӳᣬֿ϶ʡˮĥɰɫ״ҺǿҶ־õĴζ

½

ѧɷ֡κӷ֬͡ȡƷʼߣ״Ʒɵûӷ1017֬4064Լ25ҷԼ1.510״Ʒ޻еĿɴ60ϡ

ӷкϩжֶ򻯺ٶϩԼռ45DZƷԭ֬кκἰ࣬з˹ǴABCȡ

ƷɡλṲײɡλڼҺгɫө⡣˷Ӧ֮һ

ҩáӰκп֮֬κijζԳθգʹ12ˣŶԣ41530೦ͬʱк3ڲʹáӷԷų֧סտȻߣ̵̼

κͽ˸˾ãơƼãɼԤȸСθɼСȾѪβʺ֮ɳ淢ʡˮڼ飨Ȯע䣩飨УӳѪʱ䣬ŽѪԸص俹ÿѪиػʵйء佺ûijЩ񲡣ߡ

½κˮˮ-ȡҺܽʣעȮʹѪѹжݵĽ͡11000ӹǿˮ-ȡЧ߶ԶĶԾ

ơȥʣС顣

׹ۡ"ʹκھˣȾ`ҩá"

ζ¡

١Ʊݡ"ζƽ޶"

ڡҩݡ"ζ¡"

ۡջӱݡ"ȡ"

ܡ"ζȣж"

龭ΡƢθ

١׹ҩԽ⡷"θ"

ڡݾ衷"̫"

ᡶ±ࡷ"Ƣθ󳦡"

ܡҩ⡷"̫Ƣξ"

Ρɱ档֢Ʀ飬ĸʹű

١Ʊݡ"ɱС棬ȥ֢¶"

ڡǧ"һ"

ۡҩݡ"ĸ䡣"

ܡڻӱݡ"δʬ֢񱣬£űĸʹΣһަ˶"

ࣺ""

ޡݻࡷ"ţ"

ߡͨ"űֹⶾֹ"

ࡶ½вҩֲᡷ"˥ס"

÷ãҩĩҩڷ衢ɢ35֡

ע⡿Ƣθиɷ

١ݾ衷"Ƣθ֮ˣƦá"

ڡҽҪ"Ŀ"

ۡ桷"θʳ˵֮ڱ棬¶ʳйк"

һƦ֢ʳѪɻߣκǮ׽⡢ݭζ㳴Ϊϸĩ԰κȾܻΪ裬״ÿǮ¡˲ˣӵ顢ܺᣬƳ-ּ

Ʀκ㡢ûҩâϸáôƶ׽ľӶʮһȥǣɽס𡢴һǮҷʮȥڣʱˮɾϸƵʮͼ粻סֽԻƵ죬Ӳ𣬽밢κ顢ûζϸĩڽȣɸӡҩʱâϸ滼ָֽ̰Ƕãģټ֮ʱҩּ

Сʳ֩״ʹСǣκ׽һޣࣩۣǮɽһһ룬ģǽһޣһΪĩ裬ܲӴÿʮ裬¡ҽѧĿκ裩

ĸʹвʹʹ˼ʳľ㣨𣩡Ƹκô׻Ǯ롣Ϊϸĩðκӣ׷ƺΪ裬ͩӴÿʮ裬ʱƤ¡κ裩

ű֬κһͬСԴкΪ࣬ôһöȥʣȡһƬҩںڡűʱҩҸֻϣŮңҩ⣬糲ϵȥʥ¼󻢸ࣩ

ݻԡ"κ̥ɱ֮ҩҲҶԪʳУܱһȻˮ߲ˡס󡢹ȡ֮࣬ͣɻߣζлȻθʷÿöҲ"

ժ¼ҩǵ䡷


лݡκ

ҩơκ

ƴ Wèi

ӢChinese Asafoetida

Ѭκȥࡢκκ

ԡƱݡ

1.ƱݡκҶươ֭ռΪϡظΪΣԼֹΪҲ

2.ҩݡ־κʯءľҺҽ״ɫ߲״ɢΪϡϳаκ벰ߣζһ㣬ֻ޻ɫ

3.ޡκ٤۹Ҳ٤ۺΪݡ˹˹Ϊݡ

ԴҩĻԴΪɡοֲκ½κ򿵰κȷڵ֬

ֲﶯ1.Ferula assafoetida L.2.Ferula sinkiangensis K.M Shen3.Ferula fukanensis K.M.Shan

պʹأδǰա¶ԸͷжϣҺԶҶǣԼ10dҺ֬ɹ¡ٽ϶ȥһСΡ˷գÿ10d1ΣֱݽΪֹҲڴͳģڳϴȥɳ飬ѹȡ֭Һ˵Уͨﴦȥˮּá

ԭ̬ݱǿʱиҶʼ黨Ҷʣ䣻ҶĻ״ȫѣ50cmҶĩƬλԲ״Σɫ泣ëϲҶһ״ȫѡ׳ߴ2mơԻԣɡλڻɡ20-30֦ÿ֦Сɡ֦Ի͵Իɵ򣬻Ի1ƻԻɫ5С5ԲΣ5ڻꣻۻԻƣƻɫ̷ʴ2Ƥë˫ΡλΣ16-22mm6-12mmë10˿״ͻ͹ܶ3-4£4-5¡

һνݱ0.5-1.5mȫǿҵ󣬷ĴλԲ׶ΣͷдήҶά׳ͨһϡ2-5֦ëӻϷ֦Բ׶״²֦ϲ֦ͨϺɫҶҶƬ״ԲΣʽĻ״ȫѣĩƬԲΣ10mmӣϲ߳ݻdzѣɫë汻ܼĶëҶж̱״ҶСʳ״Σ뱧ɡλھ֦ˣֱ8-12cmܰƬɡ5-25ȳܱë뻨޹1-4С֦϶ϡ뻨Сɡλл10-20СܰƬΣ䣻СԲΣɫ2mmëԲ׶״Ե״ӳͷͷ״ԲΣѹ10-12mm5-6mmëͻÿ͹3-4Сȣ͹12-144-5£5-6¡

һνݱ0.5-1mȫǿҵĴζԲ׶δ׳ͷдҶάһ׳ëӻϷ֦Բ׶״²֦²֦ҶɻչʵĶģҶƬΣͬë״ȫѣƬԲΣӣ20mmƬ²ѣϲdzѻ߳ݣӣëжëҶ𽥼򻯣СҶΡɡλھ֦ˣֱ6-10cmܰƬɡ5-18-31ȳ뻨г3-5cm1-4򹣳6-15cm֦ϻСɡλл7-21СܰƬΣ䣻ϣɫԲ״Σ1.5-2mmëԲ׶ΣԵdzѻ״ӳͷͷ״ԲΣѹ12-16mm6-8mmͻÿ͹4-5Сȣ͹10-124-5£5-6¡

ֲ̬ɳءĮں850mĮкʹʯճɽϡɳĮԵԼ700mճij幵ߡ

ԴֲֲǵʺͰֲ½ֲ½򿵡

״״ 1κڣ ״۶ɴϲȵſ顣ֲڣɫһɰסơơػɫɣ޹󡣸ƷӲƷɫdzɫڿнɺɫɫǿҳ־õζ΢֮࣬ճȱˮгɰɫ״Һ

2κҪΪ½κκκʲĿ״֬״ɫdzһɫعͬɫ״ᣬʵп϶ɫdzúɫ֬״ճҰɫǿҶ־õζ֮ճѿոСˮĥʰɫҺ

״߲ɫɫԴ΢ɫζŨ־á߼ѡ

ѧɷ֡ӷͣ20.74%ɷΪR-ٶ1-ϩ[R-2-butyl1-propenyldisulfide]1([1-1-ϩ[11-methylthiopropyl)1-propenyl disulfide]ٶ3-ϩѣ2-butyl 3-methylthioa llyldisulfide)׻ѣdimethyl trisulfide)ٶ׻ѣ2-butylmethyl disulfide)ٶ׻ѣ2-butylmethyl trisulfide)-ٶѣdi-2butyl disulfide)-ٶѣdi-2butyltrisulfide)-ٶѣdi-2-butyltetrasul-fide)ȶѻǰѻΪƷζԴαϩα-pinene)ˮϩphelladrene)ʮһᣨundecylsulfonyl acetic acid)[12]㶹໯˹Ǵfarnesiferol)ABC[3]badrakemin)coladoni,koladonin),꿲ͤsamarcandin ac-etate)-polyanthinin)ì崼kamdonol)ེκأgummosin)[4]κأassafoetidin)Բ׶κǣferococlicin)[5]ȡκferulic acid ester)Ͱκᣨferulic acid)[6]

ҩá1.ã½κӷˮֹͷżʴϸѿãֱ׿鰷SRSAƽӦ

2.1.С󱻶ƤӦPCAã27ֻС3飬ÿ9ֻ1ڿԭǰ5ӻעl0mgkgɫƣһڿԭǰ30Ӹǻע50mgkgκӷˮˮȽ3Ĺֱܶ

2.2.Դ­ǹĤʴϸѿã10ֶֻ飬ϡͳ120ĴѪ0.1mlע­Ƥ֯ע24Сʱ󣬽пԭڿԭǰ30Ӹǻעˮҩ鸹ǻע50mgkgκӷˮⶨҩ­ǹĤʴϸѿ%ְκƴ­ǹĤʴϸѿ%жΪ72±7.5%κΪ31±2%Բ죨SDn5P0.01

2.3.ArthusӦӰ죺6ֻ2飬ÿ3ֻҩ4ǰעȫÿ1Ρ1עĵ7죬l%Ѱ׵0.2mlֻ6㡣۲쿹ԭ6124681224СʱھֲƤסˮ׵ֱȺͳ̶ȡƤԳѪѪں״ΪԣʮʮʮκӷˮƤ֢ӦΪԣһõArthusӦ

2.4.ûسã5ֻ1%Ѱ׵ȫ4ܺжϾѪȡسֲͬİκӷˮ1%Ѱ׵׵1mlշسӦ

2.5.ιӰ죺10ֻ2飬Brocklehurst4ܺжϾѪȡȫΰιú37Ŀ-ҺϴʵǰҩԤȸκӷ1-3ӣ510ӵĹȻ1%Ѱ׵1mlпԭ¼ͬʱιְκӷˮԿԭķʹ䡣

2.6.ԭĶԿã12ֻ2顣10%ѵշԤðκӷˮ50mg/kgθ1Сʱ4LݻIJڣ400mmHgĺ뿹ԭְκӳDZڡҩǰDZΪ100±14룬ҩǰȽŲ졣

2.7.Կ鰷SRS-A´ã18ֳֻ3飬ÿ6ֻǰ0.4%鰷2000umlSRS-A´ⶨҩǰDZڣ4Сʱֱ1%κˮҩ50mg/kgǻעͿڷҩְκˮ׿鰷SRS-A´˵κˮ鰷SRS-Aƽá

2.ӹӰ죺

2.1.ӹƽ2%øΪԣӹȫڱ״̬10ӳϴ־1.5СʱңӹлָСƵСʱԸơԴ߲10λգʾ˷ǿͣڴ˻ٴμ1‰κҺֳԵ

2.2.ãС6죬ǻע1mgκƼһĿãЧܲ롣ðκƼ10mgl-5ǻעҩԵĿŴáʵ֤ȻκδС󡢼ڹԷãԴҶء¼ӹ׿ãԻмڹΪ˷áժѳӹɼκԷãδмӹΪעƶӹãδмӹƣעƶעͪӹ˷ãδժѳעͪδмüмӹʵһ£κӹƽֱãҵڴƼˮƽϸʱκӹǿԼûСδӹ෴ã붯ͪˮƽйء

3.ã½κӷƤעڷҩԽDz˽µĴ֢͡鰷5-HTѪͨ͸нԵãʹɣκɵ֢ļԽ׶ξЧ׿֢йءƷƸɵ֢ӦʾƳٷԱ̬ӦIV͵ı̬Ӧʵ黹֤ʵκSRBCСٷԳӦDTH÷ӦϸIVͱ̬ӦΪTܰϸ鵼ԷӦ⣬κѪܰϸת3H-TdRһ֤˰κϸ߹ֱܾӵӰ졣

4.ϸѪ֯ڻã

4.1.ԴǻϸMNCcAMPcGMPӰ죺κ2550mgkgǻע2/×5죬κӸǻMNCcAMPcGMPʹcAMPcGMPıֵӡ

4.2.СѪƢ֯cAMPcGMPӰ죺κ2550mgkgÿ2ιθ5죬ⶨѪƢ֯ڵcAMPcGMPκˮѪƢ֯cAMPcGMPӰ죬ֵӡ

4.3.ƽcAMPcGMPӰ죺谢κˮ2550mgkgθ2/×5죬ⶨƽcAMPcGMPκˮƽcAMPcGMPʹcAMPcGMPıֵߡ

5.ã½κˮˮ-ȡҺܽĵʡ

6.־ɱãκͽ˸˾ã11600ơƼáɼԤȸСθɼСȾѪβʺɳ淢ʡ

1ȡƷʹܽԻƹɫɫٵμӰҺʹʼԣƣ365nm¼ӣɫӫ⡣ɡλ2ȡƷ0.5mlУԵɫϺɫټӼ䱽ɫdzУΪϺɫˮܼӰҺɼԣټˮϡͣɫӫ⡣鰢κᣩ3ȡ״жϣϵμ1ΣɲɫΪɫ

4ȡַ0.2g10ml˹ȡҺ0.2ml50mlƿУˮѴϡ̶ȣҡȣл񹲺͹ҩ1995ֹȷⶨ323nmӦա

5ȡƷڴУƣ365nm¹۲죬΢ɫӫ⣬Σɫӫ⡣

ơȥʣС顣

ζζƽ޶

龭ΣƢθ

Ρ֢ɱ棻ű֢Ʀ飻ʳظʹű

÷ڷ衢ɢ1-1.5gãҩĩҩڷ

ע⡿1.Ƣθиɷ

2.ݾ衷Ƣθ֮ˡƦá

3.ҽҪĿ

4.桷θʳ˵֮ڱ棬¶ʳйкӮ

1.ݸĿһѡƣ̷Զű꣬氢κõɰһȣ׺Ӵÿ˲һ輴ݴƣ˷ű޸ˮ£Իľ£űڻ͹ʶ

2.ݾ衷κⳣɱ棬רٶ߶أͨУϣҲ

3.ݻԡκ̥ɱ֮ҩҲҶԪʳУܱһȻˮ߲ˡס󡢹ȡ֮࣬ͣɻߣζлȻθʷÿöҲ

4.ƱݡɱС棬ȥ֢¶

5.ǧһ

6.ҩݡĸ䡣

7.ջӱݡδʬ֢񱣬£űĸʹΣһަ˶

8.ࣺ

9.ݻࡷţ

10.ͨűֹⶾֹ

11.½вҩֲᡷ˥ס

ժ¼лݡ

ղ
Ƽ