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2017-10-19 16:14 Ķ:

йҩ䡷

ҩơ

ƴBái Zh

ӢRADIX ANGELICAE DAHURICAE

ԴƷΪɡͿֲAngelica dahurica Fisch.ex Hoffm. Benth. et Hook.f.Angelica dahuricaFisch.ex Hoffm. Benth.et Hook.f. var.formosanaBoiss.Shan et Yuan ĸġҶʱڣȥɳɹɻ¸

״ƷʳԲ׶Σ1025cmֱ1.52.5cmɫɫͷλԲΣơ֧ۼƤĺͻегСаݵľۡʼʵɫҰɫԣγɲ㻷ɫλԲΣƤɢжɫ͵㡣㣬ζ΢ࡣ

𡿣1 ȡƷĩ0.5g3ml,ҡ5 Ӻ󣬾20ӣȡҺ1ml,7ǰ״Һ20ؼ״Һ23Σҡȣˮԡ΢ȣȴ󣬼ϡpHֵ34ټ1ȻҴҺ12ΣϺɫ

2 ȡƷĩ0.5gˮ3ml,ҡ˹ȡҺ 2Σֽϣƣ365nm ¹۲죬ɫӫ⡣ 3 ȡƷĩ0.5g10ml1 Сʱʱʱҡ˹ҺӸѣӴ1ml ʹܽ⣬ΪƷҺȡŷǰءŷǰضƷӴƳÿ1ml1mgĻҺΪƷҺձɫ׷¼ B飬ȡҺ4μlֱͬһȼ׻άΪϼĹ轺DZϣʯѣ3060棩ѣ3:2 Ϊչ25չȡɣƣ365nm ¼ӡƷɫУƷɫӦλϣͬɫӫߵ㡣

ơȥʣֿСԽ͸кƬ

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龭θ󳦡ξ

ΡɢʪֹͨʹŧڸðͷʹüʹԨʹ״ʹ

÷39g

ժ¼йҩ䡷

ƵĸͼƬ

ҩǵ䡷

ҩơ

ƴBái Zh

Ѧƣǡ㣨ңձݡƏ¼ƣļ־

ԴΪɡοֲ˰ţﲥֲģ79¼侥Ҷݻʱڡֲģ10²ڡ죬ȸȥϲ֣ڳоˮϴɹɻ΢ɡøﲻͨ紦棬ùá

ԭ̬˰ƣﵱ飬ۡ

ݱ߿ɴ2.5סֱִʱִ֧󣬽ԲΣԼ59ףпգͨϺɫ⻬ëжë²ҶҶĹ״ҶΪ23״ѣƬΣ26ף13ףȶ⣬ԵмؾݣӳСϲҶСҶȫ״ҶʣҶƬëҶжë.ɡλҸܻ1030ףܰȱ12Ƭ״ƬСܰ1416ƬΣȻȳȱ磻5ɫ״Σȶ˽⣬5˿ϸڻ⣺ӷλ2ң2̣ưɫɫ˫ƽԲλԲΣֹ5⣬ɳ״67¡79¡

ںӰϪߣԼغĴϡֲ֡ȵءĴӱϡϡաɽȵء

ֲҰֵĸڶãƷ""μ""

ڴƣε顣

ݱ12סֱֱ֧ԲΣпգϸ⡣Ҷ²Ҷ233ʽ״ȫѣƬΣҶ״ϲҶƬ𽥼򻯳ɹҶʣҶԵвݣɫҰɫɫëҶж̸ëɡλܻ1520ףֵȱСܰöΣСɡΪ಻ԣ5ɫԲΣȶ΢һСƬ5ҩԲΣӷλ2ң2˫ԲΣֹԵ5⣬нľʻijᡣ56¡67¡

ɽԵֲ֡Ĵɽȵء

ۺƣǫ̛嵱顣

ݱ12סԲ׶Σ4⡣ֱ47ףҶʾΪɫҶ²ҶҶ״23״ѣѻȫѣƬλԲΣȶ˼⣬ԵؾݣӳɱëëвҶСϲҶ״ҶʣСܰƬԼ5ףͨСɡ̣ɡλëȱ磻ɫ5˿Ȼ곤1.52̻ɫɫ˫ë56¡79¡

ֲ㽭̨ȵء㽭ࡣ

3ֲҶҶ๩ҩãר

ţ磬ơֲڶ

ݱȫ걻ֲڵĴëĴΡ²Ҷ߱24ףпҶʣҶƬ2״ѣ520ף57ףƬԲΣ2.55ףɫֲϸ壬dzɫԵ߲ȳϲҶ뾥²ҶơɡλͲɡ1320ܰȱ13ö״ΣСܰƬ45Σ2ͣԵϴ󣬲룬Ļ룻5״Σ5ɫȶ2ѣ5ӷë˫λΣ78ףֹ5ϸ⡣57¡810¡

ֲϡĴࡣ

״ٴƣ

Ϊֲ˰ƻ򴨰ƵĸԲ׶ζԵ⼹Լ724ףֱԼ1.52סʱ֧аݵľۣҲжͬĻ״ɫɫڶƣֲ0.51׵Ƥͻͻɫʱ֧гĺۼԵɫʼӲᡣʣȫɫ洦ܲɫ͵㣬γɲ㻷״ɫԣľʲԼռ1/3ǿ߽ܣܷ䡣΢㣬ζԶ֧ƤϸɫӲ⻬ŨΪѡ

Ĵںӱ߳ƣں߳ơơ⣬ϡɽաɽȵ

ں

ΪֲﺼƵĸԲ׶ζ⣬Լ1020ףֱԼ1.52.5ףаݵľۡһɫɫнٵƣж0.51׵Ƥͻϰ""гУ֮⣬ͻɫʱҲ֧гĺۼʼӲʣɫɫƤжɫ͵㣬γɲ㻷״ɫԣľʲػɫԼռ12ǿ߽ܣܷ䡣㣬ζԸִƤϸ㡢ŨΪѡСɡСʴΡ

۵

Ϊֲţĸֱ0.21.5ף֦򲻷֦²ϸػɫƣʱ֧ۣϲкơʴࡣƤɫɢɫ͵㼰϶γɲ㲻ԣľʲɫռȫ13ƷгɺԼ1µĺƬ㣬ζࡣ

ϡ

ѧɷ֡ŷǰأisoimperatorinŷǰأimperatorinָbergaptenɺأphellopterinǰأoxypeucedaninȡ

ơȥʣˮϴݣ̳͸Ƥ޻ʱƬ

١׹ۡ"ɵðƺ󣬹ƤϸﱣûƾϸﱣУζȷ֣һʱɹɣȥƾ֮"

ڡĿ"˲ɣƣϴأʯҰɹգΪɫҲҩ΢"

ζ¡

١"¡"

ڡ¼"޶"

ۡϱݡ"£ζ΢ʡ"

ܡҩͼ"С㣬ζ"

龭Ρ¡θ

١ҡ"θ󳦡̫ξ"

ڡ׹ҩԽ⡷"ΡƢθ"

ۡݾ⡷"ξθ󳦾"

Ρ磬ʪףֹʹͷʹüʹʹԨʪʹ©״£ӸҴƤѢ

١"Ů©³ףѪףȣͷͷ磩Ŀ"

ڡ¼"Ʒаÿʣÿʻ’к’Ż£вʹͷѣĿ"

ۡҩۡ"ĸѪʹаŮѪŻ棬ĿֹƸѪʹʴŧ"

ܡջӱݡ"Ŀ⣬̥©䣬ѪѪӸߡ硢ŧꡢѢֹʹȥ民񣡣"

ݡϱݡ"Ƥ֮磬ֹθ丹ʹʹʪʹ"

ޡĿ"αԨʹüʹ󳦷أСѪѪѣˣθʳˣ𴯡"

÷ڷ0.82Ǯ衢ɢãĩ

ע⡿Ѫ߼ɷ

١ݾע"Ϊ֮ʹ"

ڡݾ衷"Żڻ߽ᩳѪáӸ˽ȥ"

ͷʹĿʹǮͷһǮΪĩÿһ֣˻۾ʹߣȺˮô˴УЧ١ϼҽɢ

ѣΣ˲ǰէ˷аͷĿؼѪͷʹէů˼壬˺ͷĿε֤ƣ÷ϴġ飩Ϊĩۺ絯Ӵÿһ裬þϸ¡һѡ裩

ΰͷʹơϸʯࡢ㡢ûҩȥͣϸζȷ֣ΪϸĩУʹҴʹ󴵡ָùѡϸɢ

üʹ̵ƽơΪĩǮϪķ

αԨġ硢Ƹ˷֣ԶһǮ֣֣ܺϸ߷֣ʲ֡ˮ壬ļţ⡣ҽȫ

γ磺Ϊϸĩ׿¡һѡ

δأƳΪĩÿǮʮ

̴ʹѬ֮Զ쵨֭ĩͿ֮ҽժҪ

δ£аŧ¶ѣȻ긹ʹŧһҶҩߣ׷տݣУΪĩͬӴ󣬿նǼǰʮʮ裬ŧԱҩ֮塷

׶ʹ׵ĩ֮׼򷽡

ӸҳףƣƵȷ֡ΪĩǮ鷽

ε˴ƽͿ֮򷽡

ٴӦáͷʹʹʹ:ȡ2Ƭ2֣гĩڻ߱ǰͥ롣ʹ20ʹ2Чʱ1ӣ10ӣͷʹ21Ч20˥ͷʹ17Ч1427Ч԰60ˣ26ˣϸ5ˣӹƳעҺ80װ󹩼ע䣬ÿ220Ч⣬Ʒϲݡ̶١ƬͣͣƳɰͣˡ

ժ¼ҩǵ䡷


лݡ

ҩơ

ƴBái Zh

ӢDahuricae Angelica Root Taiwan Angelica Root, Root of Dahuricae Angelica , Root of Taiwan Angelica, Root of Scabrous Cowparsnip

̇ơ㡢ҡƐ

1.

2.¼ƣӶ󡣶¡²ɸظɡ

3.ͼƣ࣬ϸȣ֦ȥϡҶ涣ɫָ΢ƣӣݡ¡²ɸɡԻΪѡ

4.ֲʵͼƣߣʾƣ㣬֦룬Ҷܼ鶖ɬ̣ҿ׻

ԴҩĻԴΪɡοֲﺼƺƵĸ

ֲﶯ1.Angelica dahurica (Fisch. Ex Hoffm.) Benth. Et Hook. F. ex Franch.et Sav.cv. Hangbaizhi[A.dahurica (Fisch. Ex Hoffm.) Benth. Et Hook.f. ex Franch.et Sav. Var. pai-chi Kimura ,Hara et Yen; A. taiwaniana de Boiss. Epith. Mut; A.dahurica (Fisch. Ex Hoffm.) Benth. Et Hook.f ex .Franch. Et Sav. Var. taiwaniana (De Boiss.) epith. Mut.;A.dahurica (Fisch. Ex Hoffm.)Benth. Et Hook.f. ex Franch. Et Sav. Var .formosana (de Boiss.) Shan et Yuan]2.Angelica dahurica (Fisch. Ex Hoffm.) Benth. Et Hook.f .ex Franch. Et Sav. Cv.Qibaizhi [A.dahurica (Fisch. Ex Hoffm.) auct.non Benth. Et Hook.f. ex Franch. Et Sav.]

պʹأڵ10СѮﲥ8ѮҶήʱգȥɹɻɡ

ԭ̬1.ߴݱ1-1.5mԲ׶ΣϲΣɫжϴƤͻгУӲأɫԴ󡣾ҶʶΪɫҶһ״ѣгҶ²й״ԵĤʵҶʣϲҶ״ѣҶƬΣ15-30cm10-25cmҶ²Ϊ״ĤҶʣëϡëɫĩƬԲΣλ״Σޱ2.5--6cm1-2.5cm⣬Եвİɫʴ־ݣ߶̼ͷ򳣲ȴҶӳɳ״·Ҷ򻯳޼ġ״ҶʣëɡλҸֱ10-30cm򹣳5-20cm򹣡ɡͻж̲ëɡ18-40ܰƬ1-2ͨȱСܰƬ5-10ö״ΣĤʣɫ굹Σȶɰͷ״ȶԲ׶״Ļ2ʵԲԲΣɫʱɫ4-7mm4-6mmë⣬ԲԶ͹1͹27-8£8-9¡2.Ʊֲֵ̬뺼ƻһ¡ڣԲ׶ΣһɫԣƤĺͻɢҰɫԲԽϴںӱϵȵر

ֲڽաա㽭ϡĴȵء

ࡿѧ ϲůʪͺ㣬ɷ֣ˮõɰࡣں·ѿʵͣڱ·ѿϺã10-30Ϊѡ

༼ ӷֳһַԡ6¹ʵƤɫʱѡ֦ϽĹʵգͨ紦34½Уϲͨﲥ˲죬8Ѯ9³Ѩ35cm×15-20cmѨ5-10cm1hm2Լ11.25kgо35cmdzӾ빵ڣDZϸѹʵˮ1hm222.5kg15-20d硣

5cmҿʼ磬иݣ15cmҶ磬ÿ15-16cm1ꣻѨÿѨ1-3٪һڼ硢ͷ¢ǰ׷1Σ˷򡢸ʻصȣҲɽϽˮ

溦 а߿ݲҪΪҶ11100IJҺ࿹ù100-200u𲡣߳没Ϊ溦лƷ׳ΪҶƬڻÿ1gۺ100ڣ500ҺBt200-300Һкܲ΢Ƴ֩Ϊ

״״ ź Բ׶Σ10-20cmֱ2-2.5cmֹλ෽ΣɫжƤͻ𣬳0.5-1cmųУаݵľۡǶʵأɫԣƤܲɫ͵㣬γɲ㻷ɫΡ㣬ζ΢ࡣ

Բ׶Σ7-24cmֱ1.5-2cmһɫɫϹ⻬ƤҲͻɢ֧ۡӲɫԣƤɢɫ͵㣬γɲ㻷ԲΣɫ

Զ֧׳Ӳء㡢ŨΪѡ

΢ 棺źľ˨Ϊ10ľ˨ϸƤ͹ֲܷƤ㣬ɸȺԳʾУ͹ܽ϶ࡣγɲԳʷΡľʲռ1/2ϡɢСƷϸغеĺƴؾ

γɲԲ״ľʲռ1/3ܳʷ״С

ѧɷ֡1 ŷǰimperatorin)ŷǰisoimperatorin)ŷǰalloisoimpera-torin)ŷǰalloimperatorin)ǰأoxypeucedanin)ǰأisooxypeucedanin)ˮǰأoxypeucedanin hydrate)׵أbyakangelicin)׵ԣbyakangelicol)°׵ԣneobyakangelicol)ɺأphellopterin)ӣxanthotoxol)bergapten)5--8-ǻ֬أ5-methoxy-8-hydroxypsoralen)8--4--3-׻-2-ϩ֬أcnidilin)˨ϩpabulenol)[1-3]ȶ㶹ɷ֡޴sitosterol)ᣨpalmitic acid)ơͭп̡ơסþܡȶԪضơþơ׵ĺϸ[4]

2 㶹ࣺŷǰŷǰǰˮǰ[5]ɺأ׵ؼ-O-׻׵أtert-O-methylbyakangelicin)[6]ȣ㶹߰ࣻϻǰ߰nodakenin)3-ǻӡȘv߰3-hydroxy-marmesinin)׵--O-β-D-߰tert-O-D-glu-copyranosylbyakangelicin)׵--O-β-D-߰sec-O-β-D-glucopyranosyl byakangeliein)ݹ߰scopolin)[7]߰skimmin)-8-O-β-D-߰8-O-β-D-glucopyranosyl xanthotoxol)--O-β-D-߰tert-O-β-D-glucopyranosyl heraclenol)[8]ȣ߰adeno-sine)[7]

ҩá1.ãСθƻ򺼰Ƽl൱ҩl磩4磯k磬ƶױС֢P<0.01

2.ʹãõƤעڴñɵĸȶģͣ1ƻ򺼰Ƽ15磯k磬ԵĽáСθƻ򺼰Ƽ8磯k磬Ըǻע1%ᣨ0.lk磩µСŤԼ٣백8m磯kƣP<0.001СȰ巨飬ҩǰʹ30ߣθڰƻ򺼰8磯k磬ҩ60ӣƼƶʹֵߣˮȽP<0.0010.01

3.⾷ãƷķָءŷǰҶûسԵĽ⾷áŷǰػӹ򾼡ĽԡݹضԴƼػȻӹн⾷ãED50Ϊ0.09m磯k硣

4.ѪܵãƷŷǰغӡȘXKضèнѪѹã50m磯k罵Ͷѹ50%άʱΪ1.5СʱŷǰN-ϩͪĹʹèѹ͵ʱӳ5-10ܽĵ

5.ãƼԴ󳦸˾˾θ˾˺˾˺˾ŧ˾һͽ˸˾ȾáƷǰ11־пãŷǰпûأͽ˸˾H37RVMICΪ100mc磯mlˮ԰¶ŰСѿѢ²Ҳһá

6.ãƷءŷǰҵ߻㶹໯Ϊʣǽһܵչ䣬ʹ䴦ƤչƤףסɫӡƤȡԻΪǿ֮ŷǰҽʿư硣ŷǰΪмЧɷ֣ٴúⶨ֤Ч

7.ãŷǰغԵؾжHelaϸϸáŷǰصED50 100μ磯ml

8.ãƼ״ȡ1g/kgXǰ5Ӹǻע䣬СƤзá

9.ãСƶԶѪ˶ࡢࡢ񾭼趼˷ãʹѪѹŻ£ʹǿֱԼЪԾΣȫԡ

ԡ1.ƼθСLD50Ϊ42.88磯k磻θСLD50Ϊ53.82磯k磻СθLD50Ϊ41.97磯k磻ע仨صLD50Ϊ160m磯k硢ŷǰΪ335m磯k硢Ϊ945m磯k硣

2.ŷǰÿո״ÿ752.5m60δӰ죬𺦵ȡСƶضԶѪ˶ࡢࡢ񾭼ȶ˷ãѪѹŻµȣɲǿԼЪԾʣ֮ȫԡ

𡿣1ȡƷĩ0.5g3mlҡ5min󣬾20minȡҺ1ml7%ǰ״Һ20%Һ2-3Σҡȣˮԡ΢ȣȴ󣬼ϡpH3-4,lk 1%ȻҺ1-2ΣϺɫ㶹أ2ƷˮҺֽϣƣ365nmʪɫӫ⡣㶹أ

ơ1.ȥʣˮϴݣ̳͸ɹƤ޻ʱƬ

2.׹ۡɵðƺ󣬹ƤϸﱣûƾϸﱣУζȷ֣һʱɹɣȥƾ֮

3.Ŀ˲ɣƣϴδأʯҰɹգΪɫҲҩ΢

4.ҩԡۻơơ

ζζ

龭ΣƢθ

ΡʪֹͨʹŧðͷʹüʹʹԨʪʤкŮ״ӸҴ񣻶ҧ

÷ڷ3-10g衢ɢãĩ

ע⡿1.

2.ݾ衷Żڻ߽ᩳѪáӸ˽ȥ

1.꽣ƣƷͨã㣬ͨϣȱҲ

2.ùţͬġϸαDzɢó⣬֪ӡ

3.Ŀƣɫζϴ̫ξͷĿü֮Ҳ©Ӹ֮ʪҲɢ֮ʪԳ֮ΪҩѪ̥ŧֹʹαԨʹüʹ󳦷أСѪѪѣˣθʳˣ𴯡

4.ݾ衷ƣζ޶ң෼Ҳ̫֣Ѫ֣ڽҲ磬ʴŧ©³סɢ֮Ժ֮ƢѪףȣͷĿɢѪֹʹʳҷɢƷакʤʪҲƢֹŻ¡вʹͷѣĿ֮ЧҲ

5.ݻԡƣͷĿµֳθд֫壬ͨëϣйаͷͷʹĿѣĿ裻֫ʹԣ累ãŧ⣻ĿϣʹɬŮѪգ©Снƽ֮ζɢͷʹԡĿ©Ӹ֢ڷʪаߣ֮

6.ݾ¼֮ҩδвݺľҺߣƼ㣬ʪּܺѪݺģ֮޺Ҳǹҩ֪ҩֶ֮ҩ̣֮֮Ѫ֮ľκԶȡᣬЧѧ֮Ҳ

7.桷ƣͨбΪɢʪҩһͷͷĿʹüʹʹҲȳ˷Σ˸ԣΪԨ飻ڴ󳦣ΪѪѪգӸңʪȣƤΪɢУʹ֮Ϥȥ֮ӸDZϴɢʪҪҲ

8.塷ƣζ£ʪνɫߣΪ壬νͨ񣬿⣻ˡݡӸߡꡢѢνΪѪѪŧֹʹơνͷƤνɫζҩӸΪʪȣʪԳ֮ŧֹʹν֮ƷκʪزʪȣΪʪʮ֮Ŷ࣬ʪʮ֮һͳӸ񣬱нȻ𡣡ջӡŧֹʹһ䣬ʵУҽҩԭҽνƤߣǻʪȣְͶ֮ҩνʪԳ֮һ䣬˵ùȥ֮δᣬơڊ]塷νδ£аŧ¶ѣȻ긹ʹɰŧѪ£ŧơν֢Ǵ֮һʪ᲻ͨ긹ʹ֣亮ȷ֢йɬΪΣԻŧй֮ԵӣεΪȸŧҪҩʵ񣬱ʹԡإ꣬Ωʪʢ޻֢֮֮򲻸ԡ׷ҩ֮ɢдˣȡɢνȥpo񣣬̼֮֬壬ȻΪĿ⣬֮ߣ֮ναԨDZԨһ֢з纮ȼ֮𡣷纮飬ҲȱԨ飬ȶŧȳ֮ԨһŶۡναʹüʹȳϹΪʹŷżðƣԼйУΪ壬ΪרҪ֮ҩǴҮ£ңɢͷĿϣʪA봨ܺ޻ơŮ©³ףѪףݣʪ֢֮ʪʼΪˡ鲻㣬ʪȽΪ֢ǿɸΡͷĿᣬΩ飬纮ȳ֮ߣܺޣʢϮȣѸãľϳˣй̫ӭߣˡ֬޻ͬ¼ƷаԷ纮֮ÿʣٴνкǡʪ壬֮ξк֮طǿ֢ˡҹŽңδԴƿҲŻߣθʳ뷴֮θʢ弤ϣɐáвľУ֮֮εףqiźߣηʹͷѣΩ֮˾Ϯ֮ߣʼΪޡһѡ裬Ϊѣ֮ʵ飬ϸΪѣֲͬӡ

9.Ů©³ףѪףȣͷͷ磩Ŀ

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