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2018-10-12 10:45 Ķ:

йҩ䡷

ҩơ

ƴDn Shn

ӢRADIX CODONOPSIS

̨ºڵ

ԴƷΪ۹ֲ Codonopsis pilosula Franch. Nannf.ػΣCodonopsis pilosula Nannf. var. modesta Nannf. L. T. ShenCodonopsis tangshen Oliv.ĸ^ڣϴɹɡ

״ΣʳԲΣ1035cmֱ0.42cmɫɫͷж״ͻľۼѿÿ۵Ķ˳ʰµԲ״ͷܵĻ״ƣ½ϡ裬еĴȫһ룬Ʒ״ٻޣȫƼɢڵĺ᳤Ƥף֧䴦кںɫ״ӲԴԣƽ̹϶״Ƥưɫɫľɫζ΢

ػΣΣ1035cmֱ0.52.5cmưɫһɫͷܵĵĻ״Ƴȫһϡ϶϶࣬ƤҰɫɫľɫ

Σ1045cmֱ0.52cmһɫɫԲݹʽʵ϶٣Ƥưɫľɫ

𡿱Ʒ棺ľ˨ϸ10УʯϸȺƤխƤ㣬ೣ϶ɢеɫȺɸȺСγɲɻľʲܵɢڻۣʷ״Сϸǡ

ơȥʣϴ͸кƬ

ζʣƽ

龭Ƣξ

ΡƢΡƢļ£ʳٱ磬鴭ԣʡ

÷930g

ע⡿޼«ͬá

ءͨﴦ

ժ¼йҩ䡷


ɹеĵ

ҩǵ䡷

ҩơ

ƴDn Shn

ϵ˲ΣԭƲΣٲݾʨͷΣ󡷣ݣຣҩġ

ݴ¡

ԴΪ۹ֲ^ڣȥϲ֣ϴɹɣֻľ࣬ʹƤľʲȻɹٴ꣬34Σɹɼɡ

ԭ̬ΣɲΡҶˡҶӲݡ

ݱԲΣֱ11.7ףһĸͷ߶״ľۣƤɫɫݺơƣ磬²ɫֲӲëϲ⻬ڹ⻬Ҷ߱Ҷ0.54ףëҶƬλΣ17ף0.85.5ףȶ˶ۻ⣬λdzΣȫԵ΢״ɫַëɫܱëϸɫ5ƬƬԲ״Σȶ˶ۣ⻬ԱëڹΣֱ22.5ףɫеɫߵ㣬ȶ5ѣƬΣֱ5˿вӷλ3ң̣ͷ3©״Բ׶Σ3ң޴滨ࡣСɫй󡣻89¡910¡

ֲɽعľмԵֲӱϡɽࡢɹšຣȵء

״ҩڲزͬº֡

ԲΣĩ˽ϸ820ףֱԼ513סͷ״ͻľۣ׳"ʨͷ"ÿ۳ʰµ״һɫdzػɫݹͷнܵĻ״ƣϡԼռȫ֮롣Ƥ׺᳤ԣͻԼ0.30.8ס֧䴦ںɫ״ϵڲ֭ɡԼ࣬۶ϡƤɫ϶ľɫ⣬ζ΢Ըʴ󡢴ʵƤƶࡢζΪѡ

ڶ

ԲΣ硣1225ףֱԼ522סͷԣƤɫһɫֲڣ塣Ƥ׶̶ͻʵ״ͻɣ۶ϡƤɫľưɫƤռ֮1/3Ƥк϶ľ϶ԸʴƤɫƤʵƶΪѡ

ȵء

º

ԲΣһԼ822ףֱԼ710ףнϳߡͷ"ʨͷ"dzɫ幵ͷнϡơʽᣬ۶ϣ治΢ζԶֲ֧桢ɫס׳ֳΪѡ

ɽΪƷҰɽ̨ɽȵ߳"̨"

ѧɷ֡θ߰΢ǡǡǡۡճҺ֬ȡ

θӷ߰͡΢ǡǡ߰

ҩáٶѪϸӰ

θĴˮڷƤע䣬ʹõĺϸѪ쵰ӣժƢżƲ"Ѫ"ãƢйءʱϸм򡣱ξ޴áνҺ140ԹѪ󣬵ϸú󣬿ɱɫǡ

ڶѪǵӰ

øƤע䵳ν࣬ʹѪߣע䷢ͺĽθҩޱãΪѪкǷ£ҲעضԸѪǡݳ飬ιθѪǡ

۽ѹ

ˮྲǻע䣬ܽȮѪѹݳΪĩԵģijЩãˮҺ򴼡ˮҺҲнѪѹãࡣԸѪѹȮÿչˮҺ4ˣҩ/δнѹá

ֲͬĸȡ߰ڣ40죩ιãӺϸ17.5أ23ɽİϸ֢ԤƹЧڿڷδкβı䡣߰СڷСǿɽˮȩ֮ʿijЩ׿á

ơΣϴɳ͸ȥ«ƬжΣɹɡΣƤڼ֮ڣʱ뵳Ƭ賴ɫȡɸȥƤÿ100Ƥ20

ζʣƽ

١ԭ"ʣƽ"

ڡ¡"ʣƽ޶"

龭䱾ݡ"̫֡֡"

ΡУƢθѪʳ٣ڿʣкѸء

١ԭ"Ρ"

ڡݴ¡"Ƣθʡ"

ۡĿʰš"η飬"

ܡѧҩݡ"ѪƶѪήƲѪٲͲ"

ݡҩֲᡷ"ˣθ䣬кʣԺŮѪ̥"

÷ڷ35Ǯ12衢ɢ

ע⡿ʵа߼ɷ

䱾ݡ"͡ŭʢ߽á"

ν𣬲ԪһߣƬɳΰƬԲˮŨ֭ˮ飬ôʢ.ÿһƱĹˮҩɡ䱾ݡϵθࣩ

кѸأΣȥ«׳Ǯȡޢ˪߸һǮ֣ɽҩǮ飨ˣ֣˸ʲ߷֡Ƭ壬Ƹ֪֡ҽҪȰ

ηʿƢθΣΣˣǮһǮʲݣ֣߷֡ˮ壬·伯Ȱθɢ

СڴһưǮΪϸĩຣʡҽ鷽ࡷ

ƻɱ˾Ρ¥ݣ̰ͷƤBľƤΡ¥гϸۣٽ̰ͷƤˮΣμҺŨһܽʪΡ¥ϸۣҩҺӷ.ٽ¥ϸ۵뵷裬ÿǮأɸշΣÿһ裬ˮͷҽѧԺҽƷϻࡷ

١ԭ"ϵ˲Σ޸¾֮ȴиƽ֮಻ɳ֮ԺרйҲ"

ڡ䱾ݡ"ϵΣûʵʯֹѪʲġ۰죻ƢͣɣƤЧ֣ӹƤɡ"

ۡ塷"ܲƢθ򣬽˲βԶȿɹߣƢ˶θʪζѪƫ壬޸֮סҽɲ֮أƫᣬ֮ζ׳΢ڸߣΪк֮˺ཻҲΪܳ־ãԪ飬ÿǮֹһ֮źƽ֮ģвƾߡȻݶ磬ʷŽɷ֮˲Σ޲ºε֤֮֮Ӧ˲ߣ޲ºͶ֮

עֲͬﴨεĸͬʹãƷ""ԲΣĩϸз磬Լ1535ףֱԼ525סͷ"ʨͷ"״һɫ幵ֻнϡĺơ֧䴦֭ɵĺںɫེ״ʽϼʵ۶ϣ϶٣ľɫΧһȦdzɫƤɫζ

Ĵȵء

⣬ֲͬйҩõУܻΣ𵳡𵳣Ĵݣ̻ΣĴ뵳ΣͷΣࣩ½Σ½񵳣Ĵࣩȡ

ժ¼ҩǵ䡷


ҩĵͼƬ


лݡ

ҩơ

ƴDn Shn

ӢRoot of Pilose Asiabell, Pilose Asiabell Root Moderate Asiabell RootSzechwon Tangshen Root

ϵ˲Ρ絳ΡƲΡΡϵΡʨͷΡ

ԡݴ¡

ԴҩĻԴΪ۹ֲﳣΡػΡΡܻΡ򻨵Ρëεĸ

ֲﶯ1.Codonopsis pilosula (Franch.) Nannf. [Campanumoea pilosula Franch.]2.Codonopsis pilosula (Frach.) Nannf. Var .modesta (Nannf.) L. T.Shen3.Codonopsis tangshen Oliv.4.Codonopsis tubulosa Kom.5.Codonopsis subglobosa W. W. Smith6.Codonopsis canescens Nannf.

պʹأԺ239-10£ڳϴɹ4-6hȻʹʵ3-4δ󣬼Сػмӹڼ˷ˬ账ÿ1hm2ɻ3750-6000kg

ԭ̬1. ݡԲΣֱ1-1.7cmһĸͷ߶״ľۣƤɫɫݺơƣ֦²豻ԴֲӲëϲ⻬⻬ҶҶ0.5-2.5cmҶƬιΣ1-7cm0.8-5.5cmȶ˶ۻ⣬λdzΣȫԵ΢״ɫַëɫëϸɫƬ5Բ״Σ1-2cmȶ˶ۣ⻬ԱëΣֱ2-2.5cṃеɫߵ㣬ȶ5ѣƬΣֱ5˿вӷλ3ң̣ͷ3©״Բ׶Σ޴ࡣСΣɫй󡣻8-9£9-10¡

2.ҩ 뵳εҪڣȫڹ⻬ëƬСԼ10mm

3. ǰֵڣ²ҶШλԲۣżΣӷ²ӷԻΪȫλ7-10¡

4.ܻ ǰֵڣƣԮ״Ҷ϶̣5mm¡ӷвƬΣ1.2mmԼ8mmڵһ룻ڹ״˿ëҩ״7-10¡

5.򻨵 ǰֵڣҶƬС3cm¡ӷˣдëƬԲλ״ԲΣƬȱۣоݼë״Σɫȶ˴ɫ7-10¡

6.ë ǰֵڣ25-85cm֦࣬ľʡֲܱëʹʻɫҶϻڲ֦ϽڶҶƬСɴ1.5cm×1cm¡ܱɫӲëڳһ㲻2cm7-10¡

ֲ̬1.ɽعľмԵ

2.ں1500-3200mɽ¡ֱ߼С

3.ں900-2300mɽֱ߹Уִࡣ

5.ں2500-3500mɽز¶ʯ򹵱߹С

6.ں3000-3400ɽز¡̲ʯɺ

Դֲ1.ֲڶġࡢຣϡĴϡصȵء

2.ֲɽвϲࡢຣĴ

3.ֲϡĴݵȵء

4.ֲĴݡϡ

5.ֲĴ

6.ֲຣĴصȵء

ࡿѧ ϲ򣬼ɸ¡ϲϲ⡣ˮãֳʵɰΪˡճݵءμֲ

༼ ӷֳӷѿ80%£ų1ӣѿŽͣõһյӡԷֱڴ紺ⶳⶳǰɽУо10-15cm0.5-1cmÿ1hm27.5-15kg׸ˡȲݻɼ֦ȸDZ£18-20ң10dҳ硣Լ5cmʱ𽥳ȥڸʱעݽˮԣ1꣬^򴺼ѿǰԡ20-30cmָ6-10cmбڹڣ

DZ֤βҪʩ֮һ˱ڳӲݡ15cmʱʩ˷ÿ1hm2-15000-22500kgʩʩ22.5kg30cmʱܣʹԮ꼾עˮø

벡һ㶫^أڼ50%ɢ200Һ25%1000Һÿ7-10d1Σ2-3ΡݵغͶ꼾׷η裬ˮڿ50%в800Һࡣ˪ù40%˪300Һ70%پ1000Һ溦СԽΪ

״״ 1 ԳԲΡĴ״ԲλԲ׶Σٷ֦в֦15-45cmֱ0.45-2.5cmһɫɫɫвݹ᳤Ƥףϲ໷״ƣͷܣͷжͻľۼѿۣ״ϰ“ʨͷ”鴦ʱɼںɫ״ϵ֭ɣϡ͵㣩ӲƽеijʽƤϺ񣬻ưɫɫغɫ϶ľӴһɫľԼռֱ1/3-1/2ɫ΢㣬ζ𣬽֮

2ػ Զ̣30cmٷ֦ɫ˨Ƥֲڣ˻Ťϲܼ͵ࡣʼͣ治ƽ֮

3 ²ٷ֦ɫ˨Ƥֲ䣬ϲƽϡƤʺ϶١ζ΢ᡣ

4ܻ һ֦²з֦ݹ᳤Ƥףϲϡ裻ͷ״ʨͷ鴦غɫ״ʻʡ΢㣬ζ΢𡣣5򻨳 ʴ󣬳20-43cmֱ1-3cmݹŤϲܻƣвͷϸϰϡ“ͷ”߶ϸСľۻѿۡ1/2߷״еϸС϶

6ë ²еķֽԷԣɼ뾧㡣ζ

Ըʴ׳Ũζأ̶֮Ϊѡ

΢ 棺1 ľ˨ϸ5-8Уھƣľ˨ʯϸɢڻȺλľ˨Ƕľ˨ϸ䡣Ƥխϸ಻飬ѹǷ֯ȺֲƤ㣬֭ȺɸȺ飬У΢ԳʶͬĻ֭ܺɫ״Ƥ5-9ϸೣ϶γɲɻľʲԼռ뾶1/2-4/7ܵ5-10ۣг1-2Уľ߿㣬γɽϴ϶ľг1-2ľ߿㣬γɽϴ϶ľϸнܣľʲԭ͡ƷϸǼ

2ػ ľ˨нϺľ˨ʯϸеľֲ䣻ƤԼռ뾶2/3ľʲСܴСһͬ״Ʒϸǡ

3 ľ˨ϸ񣬾ƿףľ˨ʯϸųɶĻеǶľ˨ϸ䣻ƤԼռ뾶2/3ľʲСľϸе񡣱ƷϸΪǴ϶С4ܻ ľ˨ϸ3-7УƤϸԵϸ϶ľʲռ뾶1/3-1/4ܶ൥ɢڣƷϸƤĵֱ13-16μmΪľʲĵֱ4-7μmΪҪֲľʲϸ뵼ܰ

5򻨵 ľ˨ϸ5-10УƤռ뾶5/8߿5-7ϸľʲԼռ뾶3-8ľϸ񣻱ƷϸǣڵΧڰеŵС

6ë ľ˨ϸӳ164μmƤľʲȾľ߿㣬Ƥխ2-4ϸ

ĩ1 ưɫپǶ࣬ˮȩҺװãſԳΡԲλԲΣ߷״ơʯϸ϶࣬ɢڻȺеľ˨ϸǶʯϸΣ෽Σλ򲻹Σֱ24-51μmƿϡ衣۾Եƿסơ״ԵҲܼƵܣֱ21-80μmܷӳ80-88μm֭Ϊн֭ܣֱ12-15μmмΧϸг͵״Pϸľ˨ϸػɫ۳ΡбλΣܱ΢״ľơ⣬ɼ

2ػ ɫʯϸֱ࣬19-60μm35-107-256μmں񱡲ȣƿϡ裬׹ԣеĿ׹ܼݺύ״״ľϸ״״״񡣢ɫؿɫغɫеijڵСܵԲλԲΡ

3 ɫʯϸ٣ֱ25-36μk60-76μmں3-5-8μmевڽϺʹǻ״׹ԣ԰״©״ľϸΣеƽܱϾ״еĴܱڳ״еƿס׹ԡ۵϶࣬ԲΡԲΣֱ6-20μm״Ϊ2-7ɡ

4ܻ ɫٵ࣬ԲλԲΣֱ6-30μmѷ״״״ԣ븴2-3㣻2߳ɣС⡣ľ˨ϸλ򳤷Σɴ80-100μmľľϸΣڳ״״״

5򻨵 ưɫľ˨ϸ۳λбΣеĴܱ״񣬿׹ԡľϸλΣ״״񣬲ڳ״ϸй򣬾ϸΣϡ¶˾еķ룬״񡣢ܺϸʯϸ״ƿס׹ԣڷľɫؿ׷磬طɫʻɫ

6ë ɫľ˨ϸ೤Ρλ෽δܱڿɼơľϸϸΣڳ״״񣬲ڳ״ɫؿ顣򻨵ơ

ѧɷ֡1.3.4910.530.48ɣԷ10 500CPǡǡǡǡ¶ǡǣriboseľǰĦǡǡǡǡ¶ǡǣrbioesľǰĦ1.7710.430.260.120.0230.013ɣԷ12000CP3ǡǡ¶ǡǡǡǡľǰĦ5.944.431.071.0720.200.13ɣԷ14 000CP4ǡǡǡǣrhamnoseǡ¶ǡľǰĦ1.510.60.460.290.130.06ɣԷ79 000[4]߰ɷ֣߰syringinѻ-β-D-߰n-hexyl β-D-glucopyranosideһ-α-D-߻ૹ߰ethyl α-D-fructofura-noside[5]߰tangshenosideͺɷ֣choline[7]ݼperlolyrine[8]n-butyl allophanate[9]ȰN-߰pyro-glutamic acid N-furcto-side[10]ᣨnicotinic acid5-ǻ-2-़״5-hydroxy-2-pyridine methanol[5]ԼᣨlysineհᣨthreonienӰᣨvalineᣨmethionineᣨsioleucineᣨleucineᣨphenylalanine춬ᣨaspartic acid鰱ᣨhistidine˿ᣨserineȰᣨglucamic acidʰᣨglycineᣨalanineװᣨcystineᰱᣨtyrosineְᣨarginineᣨproline17ְ[1]޴Ƴɷ֣ѹӢtaraxerolѹӢ޴taraxerl ac-etatefrideelin[9.11]α-spinasterolα-޴β-D-߰α-spinasteryl-β-D-glucoside7-ϩstigmast-7-en-3β-ol7-ϩ-β-D-߰7-sitgmas-tenyl-β-D-glucoside޴stigmasterol޴-β-D-߰stigmasetyl-β-D-glucosideα-ͪstigmasta-7,22-dien-3-one522-޶ϩ-3-ͪstigmasta-5,22-dien-3-one[1213]ɷ֣ȩsy-ringaldehydeᣨvanillic acid2-߻ᣨ2-furan car-boxylic acidatractylenolide򼰢[3]5-Ǽ׻ȩ5-hydroxymethl-2-furaldehyde[714]5-׻ȩ5-metyoxymethy-2-furaldehyde[14]methylpalmitate[12]Լͭܡ̡пȡ޻Ԫ[115]ӷͣһֱƣɷΪռ28.04%αϩα-pinene24-ɶϩȩnona-2,4-dienalԣborenolξ-ľϩξ-guaieneα-ϩα-curcumene32ֳɷ[16]һƣк66ɷ֣ɷǣᣨpalmitic acidռ38%1114-ʮ̼ϩmethyl11,14-eicosadenoateռ9.89%-ڼ[O-O-methoxyphenoxyphenol]ռ5.74%[17]

2.ػ հᡢӰᡢᡢᡢᡢᡢ鰱ᡢŶᡢ˿ᡢʰᡢȰᡢᡢװᡢҰᡢᡢְᡢ17ְ[18]

3. [2]ѹӢѹӢ޴ƣ޴[9]߰[20]߰񡢢[20]󡢢[21]E-2-ϩ-β-߰[E-2-hexenyl-β-sophoroside]E-2-ϩ-α-L-૰ǻ1→6-β-D-߰[E-2-hexenyl-α-L-arabinopyranosyl1→6-β-D-glucopyranoside]ѻ-β-߰hexyl-β-gentiobiosideѻ-β-߰hexyl-β-soporoside6R7R-EE-ʮ̼-412-ϩ-810--167--6-O-β-D-߰[6R7R-EE-tetradeca-4,12-dien-8,10-diyne-167-triol-6-O-β-D-glucopyranoside][21]codonolac-toneDz󣬵ᣨcodopiloic acid[22]Լ춬ᡢհᡢ˿ᡢʰᡢȰᡢᡢװᡢӰᡢᡢᡢᡢҰᡢᡢᡢ鰱ᡢְᡢȰ[18]ͭܡп顢⡢޻Ԫ[15]

4.ܻ ͭܡ̡п顢⡢޻Ԫ[15][2]

5.򻨵 ιӢҴѹӢơ޴[19][2][23]춬ᡢհᡢ˿ᡢʰᡢȰᡢᡢװᡢӰᡢᡢᡢᡢҰᡢᡢᡢ鰱ᡢᡢȰ[18]

6.ë [2][23]

ҩá1.ϵͳӰ죺1.1ԶѧϰӰ죺 С̨ʹʽӦ-̶ʲ۲˵20%ҴȡѧϰӰ죬ο׿ݹмɵСòɵС乮ϰ40%ҴɵСȱ𣬲ֶԿݹмԴ̶ʲơνһֿáֶM׺ʹMܶߡȲܶԿݹмСƤ㼰AchĽ͡䱾ҲƤͺAchЩʾζѧϰȷиãͨ·䷢õһҪ档μYˮ·͸Сѧϰ̣ܸļϰӰ졣

1.2ԷӰ죺 MKһANIEX¼ǣͬʱ¼2ֻС4ڵԷμ飺Сn=22ֱ0.150.6g/10gˮθⶨ2СʱԷζСԷá

1.3ȡСЭͬСȱີã׿ȱີáˮӳͼ30mg/kgͱƵС˯ʱ䣬޴áˮʹʹͱС˯ʱ̡⵳ȡӡغĵһ׿ãʹСľʺʱӳʿԵĶԿáбζϵͳҪĵζǡ

1.4ȡԼԵͼӰ죺 ڴص缫Ѽϣ۲쵳θλȡƤ㼰ƤԵͼӰ졣θλȡѼԵͼáҸҩλ򡢢ˮ߰áҩʱֻвλʹѼԵͼָ߷òλ߰֬Եġβλȡ򡢢ˮ߰뺣ӰƴƤ㡣λ˲߰ŵӳС󻷼ͱ׵˯ʱ䡣

2.Ѫϵͳã2.1ѪҺѧã ȡãֱ뵳Σˮ崼Ƴ11עҺ1ml/kgõˮ30ӺⶨѪҺѧĸָꡣѪ˨γɣҩǰȽԵѪ˨γɣP0.005-0.001ѪҩǰԸı䣬ϸѹҩǰֱΪ38.01±3.9834.21±4.87p0.005ϸӾѪճȵȵҩǰŲ죨p0001

2.2ȱã ˮᴼƵõĵעҺÿ1ml൱ҩ1gСҩ鸹ǻע0.2ml/10gѹȱԵĶԿ븹ǻעˮ0.2ml/10gȽϣp0.001غԶԿãˮȽp0.05軯жӳСʱp0.001ԽСྱܶʱ䣬ʮӳʱp0.001

2.3ԼúʹʵԼļȱѪӰ죺ԤԸҩԸҩ۲ĵͼTS-Tελƺʵı仯100%עҺԴµļļȱѪһıá

2.4Զ΢ѭϰӰ죺 ȡ20ֻˮĤ΢ѭϰٷֱõκˮչ۲΢ѭĻָÿ10ֻãõκ80%15ʱ΢ѭѻָҹܾ״̬30Ӻȫָ΢ѭĿ״̬ܾ࣬ˮ״̬΢ѭ뵳Բ죬ˮ΢ѭϰˮ15ʱһָ30ʱֻٲֽϴѪģɼ

3.ϵͳӰ죺3.1οã3.1.1.ԴӦӰ죺 ζǸڴڷ50mg/kg250mg/kgӦθзdzԵãp0.001μ20g/kgˮӦɵĴзdzԵáôˮӦģͣθֲθ缫Ͱ뵼Ӧ淨۲쵽Ӧ״̬£θңθ˶ǿθſԼӿ죬θˮ崼Һ40g/kgӦθбãͬʱθθ˶ı仯

3.1.2.Žģ͵ıã ڷζ500250mg/kg ŽʵθһıáμҺ20g/kg͵ȡ5.0g/kgԴŽθԵԤãp0.01

3.1.3.ˮҴ˴θճĤıã μԽˮҴθճĤˣձȽ˷Ϊ40%100%ָΪ147.8±59.38Ϊ8.95±15.59p0.01,ʴ93.94%

3.1.4.ʹ˹ƥ´θӰ죺 ζ500mg/kg͵ȡԵãp0.01ʹͰ˹ƥĴθճĤPGE2ͰǺ½ԵĶԿãԴθԵãɶԿ˹ƥθҺH+Ũ½Na+ŨߣʹH+/Na+ݱֵ;Թ1×10-2g/mlĵȡ΢ڻϩᣨAAлϵͳмá

3.2μЧɷֿθճĤ˵ûƣ βλȡ-ڷ θڽճҺʮָҩŽθڽճҺڷ3СʱԼˮҴµĴθճĤ˺θճĤλ½ʹָͺ˺θճĤλͰٷ½10-40g/kgؼ¾ԵЧϵ1020g ҩ/kgؿڷʹŽθճĤԺ½ҩθҺڵйأСڷԼ׻θſ˶Ӱ죬ԼʮָԷƣ׿µļ峦ܵǿֱ

4.߻ܵӰ죺μǿʹϸӣϸα࣬ǿϸڵDNARNAࡢACPøATPøøøԾǿ΢ֹȼƲⶨҩ󣬾ϸڸֻѧɷֺӣԲ졣λԴٽConAܰϸDNA͵ʵϳɣٽDNAϳɵŨΪ100μg/mlDNAϳɵĸ߷48Сʱ԰׽-2IL-2ҲԵǿá

5.ãʹѪѪɫӡСƤעl00%ˮҺ0.2mlС󿹸ŨΪ4mg/mlŨʱܰϸ˿дٽãȽϴļ˿ѡλʹСѪƤͪӡѪʾβɽͻӹãÿҩ˷йءζԴƤϵͳ˷ܺ͵áǶԷбõĻ

ԡˮҴעҺСǻעİΪ79.21±3.6g/kgС1οڷζ10g/kg۲72СʱҲԱ仯

1ȡƷѽӴܽ⣬عܱڼŨᣬҺɫ壬ϲɫΪɫֲ޴2ɫ ٱƷĩȷ»ȡȡҺɣȷҺΪƷҺȡҺҺͬһ轺GF254ϣԻ-73չΡҺ1105minƣ245nm¼⡣μƷҺɫƷɫӦλϣʾͬĵɫӫߵ㡣ڱƷ״ȡᆳȥ֬ΪҺԶ߰syrigin״ҺΪҺȡҺҺͬ--GF254ϣȷ-״-ˮ7305չΡƣ254nm¹۲ӫ⣬ҺɫҺɫӦλʾͬİߵ㡣

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2ΣƤڼ֮ ʱ뵳Ƭ賴ɫȡɸȥƤ(ÿ100Ƥ20)

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ΡƢΡƢθʳٱ硢֫鴭ȡԺ΢֤

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