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2017-05-24 14:01 Ķ:

йҩ䡷

ҩơ

ƴFán Fn

ӢRADIX SAPOSHNIKOVIAE

ԴƷΪɡοֲSaposhnikovia divaricata Turcz. Schischk. ĸδ黨ֲĸȥɳɹɡ

״ƷʳԲ׶λԲΣ²ϸе1530cmֱ0.52cmɫֲڣơ᳤Ƥ׼״ͻϸۡͷܼĻƣеĻϲдغɫë״Ҷᣬɣ۶ϣ治ƽ̹Ƥdzɫ϶ľdzɫ죬ζ΢ʡ

𡿣1Ʒ棺ľ˨Ϊ 530ϸƤխ,нϴԲ͹ܡƤϿжԲ͹ܣΧϸ48ڿɼɫ߶ೣ϶γɲԡľʲ࣬ʷ״Сͷ裬

֯żʯϸĩɫ͹ֱ1760μmɫҶάάƵֱ1485μmʯϸټɫԲλ೤ΣڽϺ

2 ȡƷĩ1gӱͪ20ml20ӣ˹ҺɣҴ1mlʹܽ⣬ΪƷҺȡҩ1gͬƳɶҩҺȡպ5-O-׻ά˹״նƷҴƳÿ1ml1mgĻҺΪƷҺձɫ׷¼ B飬ȡҺ10μlֱͬһ轺GF254ϣȷ-״41Ϊչչȡɣƣ254nm¼ӡƷɫУҩĺͶƷɫӦλϣͬɫİߵ㡣

ơȥʣϴ͸кƬ

ζʣ¡

龭סΡƢ

Ρ磬ʤʪֹڸðͷʹʪʹ˷硣

÷4.59g

ءﴦ

ע1Ϊɢ纮ܷɢȣ뾣£ҩӦáʪֹʹǼƷʪʹ֢˷磬ֹãǡ顢׸ӵҩͬá⣬ƷֹѪֹкãڸʹйкϰ֡זXƤͬãڱѪ©һ㳴̿Ӧá

2һҩ˼壬ηֹʹҩ纮ʪֹʹ΢¶ҩԽΪֿͣڷӸʢĿʹʺ֢뾣桢ɡ̡ɽ١˵ͬá⾷棬˷磬ƷֻΪҩܶ书糣֦ͬԷҲȡáɢ֮顢ýΪ͡ھҩȣ򾣽淢֮ǿֹʹ֮Ϻáٴᣬ糴ÿɼȴֹкĹЧڸк糴ֿ̿ڱ©Ѫɫ嵭ߣ¾ֹѪڽȣƶѷ

ժ¼йҩ䡷

ͼƬ

ҩǵ䡷

ҩơ

ƴFán Fn

ͭܿܿݡ̸֦㣨ձݡ磨¼⣨ҩϻࡷ

ԴΪɡοֲɲڣڳ󣬳ȥҶɹ˳ɸɣѺɹɡ

ԭ̬磬ɽëݡ

ݱ3080ףȫë׳ɫά״Ҷл2֦Ҷ״Σ719ף23״ѣƬΣȫԵҶ26.5ףҶ򻯣չҶ.ɡλ򣬶ɡ59ȳܰƬȱ磻Сɡλл49䣬СܰƬ45ΣݶΣţ5ɫΣͷھӷλ2ң2Բ׶Ρ˫Σʱ״ͻ𣬳ʱѿ2ֹڶĶˣֹ⡣89£910¡

ֲҰشɽ²ݴУߡ·ԣɽС²ֲɹšӱɽϡɽϵȵء

״ĸԲ׶λĴΣ2030ףͷֱԼ1ףвֱ11.5סһɫɫͷܼϸڣɫëоIJкۣƤֲڣв弰ϸƣɢۻɫĺ᳤Ƥ⣬״ͻҲ洦ɼɶ۶ϣ϶ƽ̹ľɫƤɫ϶߳ʷ״΢㣬ζ΢ʡ׳ƤϸëͷɫɫΪѡƤֲڡëͷӲʴΡ

ں֡ɹšӱ⣬ɷҩɽɽȵԺƷУ֡ɹţij"ط"""Ʒѣɹţӱе¡żҿڣ"ڷ"ɽ""Ʒʴڹط磻ӱɽɽij"ɽ"ֳ"Ʒ"""ƷϴΡ

ѧɷ֡纬ӷ͡¶ζ߰ȡ

ҩáٽ

˹ȼãڸطԽãýϽá

ʹ

С磨Ʒδ50ҴҺȥҴʹУ̼βƤעͬЧ

ۿ

ʹطեҺ飬ŧ˾ɫһáƷδķѪ˾ҲһĿá

ط紼Ƥע䣬ѪӰ졣

𡿱Ʒ棺ľ˨Ϊ 530ϸƤխнϴԲ͹ܡƤϿжԲ͹ܣΧϸ48ڿɼɫ߶ೣ϶γɲԡľʲ࣬ʷ״Сͷ裬֯żʯϸĩɫ͹ֱ1760μɫҶάάƵֱ1485μʯϸټɫԲλ೤ΣڽϺ

ơ磺ȥоˮݣ̳͸Ƭɹɡ磺ȡƬù΢ɫȡ

ζʣ¡

١"ζʣ¡"

ڡ¼"޶"

ۡҩƷ塷"ͣζ΢΢¡"

ܡ¡"ζƽ޶"

龭סΡƢ

١ҡ"̫ҩ"

ڡҺݡ"θ̫Ƣ֮оҩ"

ۡ׹ҩԽ⡷"ξ"

ܡ¡"ΡƢ"

Ρ磬ʤʪֹʹз纮ͷʹĿѣǿ纮ʪԣǽʹ֫μ˷硣

١"ͷѣʹ磬аĿäǽ۱ԣ"

ڡݾע"ɱӶ"

ۡ¼"вʹвͷȥ֫μھ"

ܡջӱݡ"ʮ磬һӣ񣬷ֹۣἰ̱ͨˣķأܰ־"

ݡҡ"ȥϷ磬ңȥ·硣"

ޡҩ෨󡷣"ηͨáкʵɢͷĿϽа"

ռ"Ѹ"

ࡶɳҩ⡷"о磬ʪͨؽڣֹʹ켱Σ֫ڣ̱Ժ©¡С"

ᡶԭ"ͷܾҰҩ"

÷ڷ1.53Ǯ衢ɢãĩ

ע⡿Ѫ龷ͷʹа߼ɷ

١ݾע"ɽ޼«ܾ"

ڡƱݡ"ηZ"

ۡݾ衷"Ѫ龷ͷʹڷ纮йںʪɬСƢ鷢Ƣ磬ŻԣԺȲͬɡ"

ܡ䱾ݡ"Ԫ飬ʪ߽á"

ءﴦ

ηак磺硢桢֢Ρ

ƫͷʹʪĿʹֹܺǮǮ磨ȥ«Ǽһ˸ʲһǮȥƤﱣһƣһ보ΪϸĩÿǮذյ࣬Ĩڿڣð¡ԣͷʹÿϸ֡زءոࣩ

ƫͷ磬ʹߣ硢ƸΪϸĩۺ裬絯Ӵ綾ֻòΪ裬ÿһ裬¡ƫͷ磬ķ磬ʳδռ÷

ηȷо룬֫役ͷĿѣǿʹڿɣɲƦƣŻٳճθȽᣬܱյ֢硢ܺ顢ҩơҶợâʯࡢˡ۹һʯʲݶ桢Ӹ-֡ΪĩÿǮˮһյƬ֣·۷ͨʥɢ

ΰ׻磬תʹϥףһȥ«ͷ΢΢©«ϼҩϸΪɢÿʱ¾Ƶ¶Ǯʥݷɢ

Ӹտߣ硢ơʲݡ֡ܺβǮһڡаˮ壬ԾƬպˮϴ֮øɣȻҩëϴ֮ʮ

һз累ѢƤɦ磨ȥ棩ǡԣˣȥƤӣһ룬ζΪϸĩþ쵷ãԾưΪ̶࣬ÿʮ裬ƻ¡ʥ¼裩

˷缰ǣϴߴΣ磨ȥɣȷ֡ϸĩҩڣȻ¾ƵһǮؼǹţҩǮͯС£֮ˣҩǮ¾Ƶ¡·ɢ

Ժ硢θһÿǮˮһӰ룬ƬϪķɢ

εǮܺǮ룬˲һǮְ롣ΪϸĩÿǮ¡ҽЧɢ

˳˴ɬ硢׿ǣﳴһʲݰΪĩÿʳǰǮ㵥

αУȥ«ͷΪĩÿǮƵ£Ͷ֮󷽡

ùף硢ꪡҶǮˮ壬ѬϴÿһΡݡ鷽ҽƷ

עƷ⣬¼֣Ϊϰҩ

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Ҷ

ΪֲͬҶĸ"Ҷ"

Ʒ

ΪֲͬҶĸϡĴֲ30100ףϸơҶΪ2ػ3سѣƬλ״ΣвϾҶҶʡɡλ򣬻ӳӲܰҶ״ܰ1Ƭɡ68̲һСܰƬԼ10ƬȱڻɫΡ

½

ΪֲͬϸҶĸ½ֲ12סҶ3״ȫѣƬΣҶСɡλɡȳëܰ510ƬΰƬ汻ëСɡλлͷ״Сܰ67ƬСƬݶ̣˿״ɫԲΣë

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ҩơ

ƴFán Fn

ӢDivaricate Saposhnikovia Root, Root of Divaricate Saposhnikovia

ͭܿơزݡ֦֡硢

ԡũݾ1.¼硢ɳԷ󼰺ϲ̡¡ʮ²ɸɡ

2.պ뾰ɳԷ񣨷磩һ꣬ߣݻ֮γؽ磬ãϲߣΩʵ֬ͷڼͷΪá

3.ƱݡݣɽƣݡݡѡҶĵȡ¼ƣͷ˷񣬲β߷󼲣ƺݴ

ԴҩĻԴΪɡοֲĸ

ֲﶯSaposhnikouia diuaricata (Turcz.) Schis-chk.[Stenocoelium diuaricatum Turcz.; Siler diuaricatum (Tur-cz.) Benth. Et Hoo. F. ; Ledebouriella seseloides Auct. Non Wolff; L.diuaricata (Turcz) Hiroe]

պʹأһڵؿֵ2Ķջѡزƣ3-4ջ񡣲ںȥоɹųɸʱϸ̷ֱСɹ򿻸ɡ

ԭ̬ݱ30-80cm׳ԲΣз֦ƹɫбȳϸ⡣ҶбⳤҶпҶʣԱҶƬλԲΣ14-35cm6-8-18cm״ѣһƬλԲΣб5-8cmڶƬ²߶̱ĩƬШΣ2.5-5cm1-2.5cmҶ仯пҶʡɡλھͷ֦ˣ򹣳2-5cmɡ5-73-5cmëܰƬСɡλ4-10СܰƬ4-6λΣԼ3mm״Σ굹ΣɫԼ1.5mmëȶ΢СƬ˫ԲλԲΣ4-5mm2-3mmʱ״ͻ𣬳ʱƽÿ͹1͹28-9£9-10¡

ֲ̬ڲԭͶɽϡ

Դֲֲڶࡢġɽȵء

ࡿѧ ϲˬͺ͸ɺѡ㣬ɷ֡ˮõɰ࣬Դճصֲ

༼ ӡ己ֳӷֳ3Ѯ4Ѯﲥ9-10½Со30cm2cmӾȲ빵ڣƽDzݽˮ20-25dɳ磬1hm215-30kg己ֳջʱ紺ȡ0.7cmϵĸس3-5cmΣ50cm×15cm1hm2ø750kgҲɽָڶ10cm×50cmֲ磬紺1-2ƬҶʱԶֲ

5cmʱ7cm磬10-13cmʱ13-16cm硣6ǰݡ6Ѯ8Ѯ׷1Ρֲ꣬⣬Ӧʱժ̦

溦 İ׷۲ġ^Ϊʱ粨0.2-0.3ʯϼв800-1000Һ25%1000Һ溦лƷ5¿ʼΪ90%аٳ800ҺɱƳٿڷ糿90%г800ҺBt300ҺΡ

Ϊ

״״ ʳԲ׶λԲΣ²ϸе15-30cmֱ0.5-2cmɫֲڣơ᳤Ƥ׼״ͻϸۡͷܼĻƣеIJܼĻƣеϲдغɫë״Ҷᣬɣ۶ϣ治ƽ̹Ƥdzɫ϶ɢɫ͵㣬ľdzɫ죬ζ΢ʡ

׳ƤɫdzءľɫdzΪѡ

΢ 棺ľ˨Ϊ5-30ľ˨ϸƤխнϴԲ͹ܡƤϿжԲ͹ܣΧϸ4-8ڿɼɫ߶ೣ϶γɲԡľʲɫ߶ೣ϶γɲԡľʲ࣬ʷ״Сͷ衣֯żʯϸ

ĩɫ͹ֱ17-60μmɫҶάάƵֱ14-85μmʯϸټɫԲλ೤ΣڽϺ

ѧɷ֡ɫͪɷ֣ɫͪlede-bouriellol)4′-O-ǻ-5-O-׻ݰܴ4′-O-glucosyl-5-O-methylvisamminol)3′-O-ӣ3′-O-angeloyl-hamaudol)éӣhamaudol)3′-O-éӣ3 ′-O-acetyl-hamaudol)é߰sec-O-glucosylhamaudol)5-O-׻߰״5-O-methylyisamminol)أcimifugin)߰prim-O-glucosylcimifugin)㶹ɷ֣bergapten)֬أpsoralen)ŷǰimperatorin)ɺأphellopte-rin)¶deltoin)[12]أxanthotoxin)[2]anomalin)[3]ݹأscopoletin)[3,4]ӡȘXKأmarmesin)[4]Ȳɷ˲Ȳpanaxynol)ֳҶ۴falcarinol)Ҷ۶falcarindiol)8E-ʮ̼-18-ϩ-46--310-[8E-heptadeca-1,8-dien-4,6-diyn-3,10diol][2,5]Զǣsaposhnikovan)AC[67]ӷͺ10ֳɷ֣ܼĹ20֣ϸߵȩoctanal)β-ûҩϩβ-bisabolene)ȩnonanal)7-ϩ-4-7-octen-4-ol)ȩhexanal)ϩcuparene)β-Ҷβ-eudesmol)[8]β-޴β-sitosterol)β-ȴ-β-D-߰β-sitosterol-β-D-glucoside)[3]¶mannitol)ᣨvanillic acid)[4]ȡ

ҩá1.ʹ:1.1.ԴСŤ巴ӦӰ:ȡ18-21gС24ֶֻ飬ֱpoˮ1ml2gҩ40g/kgͬˮ1Сʱip0.5%0.2ml/20g۲20СŤ巴ӦСŤ巴ӦΪ11.4±1.8ΣԵڶ19.2±2.4ΣP<0.05

1.2.СʹеӰ:Ȱ巨ⶨʹУȰ¶Ϊ55±0.5档ȡ18-20gС󣬾ԤⷴӦDZںѡ䷴ӦDZڲ30sС20ֶֻ飬ֱpoˮ൱ҩ40g/kgͬˮⶨҩǰСӦDZڣ2СķӦDZڷҩ60s90sӳP<0.05

1.3.̼β:̼βҴСig21.18g/kgsc42.36g/kgһʹãҩʹʷֱΪ46.4%56.7%60Ӻʹֱ39.O%53.3%

2.:2.1.ͱ˯߼Ӱ:ȡ20-28gС40ֶֻ飬ֱpoˮ൱40g/kgͬˮ1Сʱipͱ35mg/kg¼15ڶ˯Էʧ1Ϊ˯ָꡣ˯С17ֻ85%ȶ飨17ֻ35%ӣP<0.01

2.2.СԷӰ:ȡ20-22gС24ֶֻ飬ֱpoˮ൱40g/kgͬˮ50ӣ¼10СΪ226.3±35.9Ϊ326.7±27.7ɼʹСԷԼ٣P<0.01

2.3.:ȡ24g-26gС20ֶֻ飬ͬϣlСʱðͶͺϼ25ulͿҶף4СʱС󣬳ز۲֢Ӧ̶ȡͳ̶ȣ13.9±0.9mgԵڶ飨18.4±1.2mgP<0.05

2.4.־:ƽ巨־ʵ飬ԽɫѪ˫ùùɫù־ãи˾˺˾ϼ־˾־á

5.:5.1.24-ȱDNCB³ٷͳӦӰ:ȡ25-28gС20ֶֻ飬5%DNCBͪҺ0.01mlƤһΣ5쿪ʼҩСÿpo20g/kgͬˮҩ7죬ĩθҩ1%DNCBͪ0.02mlͿҶ20СʱСȡҶƬֱ8mmأԶƬ֮ʾٷͳӦij̶ȡΪ2.90±0.45mgԵڶ4.88±0.78mgP<0.05˵DNCBµijٷͳӦá

5.2.ܡسƽӰ:ȡ250g-350g10ֻÿֻǻע5%ѵ1mlͬʱȸע0.4ml4ܻܺسƽ顣2.8±0.5mmȶ飨7.8±0.7mmԽ͡س10λس߶Ϊ31.8±4.3mmȶ10λس߶ȣ42.4±5.2mmԽ͡

6.СǻϸɹܵӰ:ȡ23-25gС24ֻ2飬ÿigҩ1Σ4죬ĩθҩͬʱip5%ϸҺ0.5mlٴϸɰٷʺָ

7.:磨տȡ׺˷磩Ƴɶģ͡IpطˮҺ2g/kg԰ƥֺˮաˮҺ1-2Сʱڽԡ

ԡȡ18-20gС۸룬4飬1ηֱigͬķ磬۲5ɶ򻯻ʵλLD50LD50Ϊ213.8±25.4gҩ/kg

ơ1.ȥоˮݣ̳͸Ƭɹɡ

2.磺ȡƬù΢ɫȡ

3.̿ƣȡƬùڣлʺɫڳʻƺɫΪȡˮ𾡻ǣȡһҹ

4.ˣȡ磬۳۱伴ɡÿƬ1kg0.3kg

ζζʣ΢

龭ףΣƢξ

Ρʤʪֹʹ⾷ֹз纮ͷʹʹʪʹǽʹʹйкѪ˷磻

÷ڷ5-10g衢ɢãˮѬϴ

һãֹкãֹѪ̿á

ע⡿Ѫ龷ͷʹа߼ɷ

1.ݾעɽ޼«ܾ

2.ƱݡηZ

3.ݾ衷Ѫ龷ͷʹڷ纮йںʪɬСƢ鷢Ƣ磬ŻԣԺȲͬɡ

4.䱾ݡԪ飬ʪ߽á

1.2.ζǼ(֪)ʪȣз纮ʪа3.ɢ(Ϫķ)̱αԺ׸за4.ɢ(ڡ)Ѫȳʪηʪ5.ܺɢ(̫ƽͼַ)ֹʹзаͷʹ6.ɢ(ڡ)Ч绯̵

1.ͷѣʹ磬аĿäǽ۱ԣ

2.ݾעɱӶ

3.¼вʹвͷȥ֫μھ

4.ջӱݡʮ磬һӣ񣬷ֹۣἰ̱ͨˣķأܰ־

5.ҡȥϷ磬ңȥ·硣

6.ҩ෨󡷣ηͨáкʵɢͷĿϽа

7.ùţѸ

8.ɳҩ⡷о磬ʪͨؽڣֹʹ켱ϣ֫ڣ̱Ժ©¡С

9.ԭͷܾҰҩ

10.ҩԡ磩ôак޻Ʒ磬õ顢ҩʯƸӲط硣

11.꽣磬һʹ˷ҩҲƢθǴòСʹǿɻعˡۣưߣ̫֤÷硣ϣ̫֤൱֮Ϊɢȥϲ硣о߷Ҳ֤֮Ǯкɢб÷ߣкľҲƻΣε÷书ηʹҲ

12.ݾ衷ηͨãɢͷѣʹаǽ۱ԣвʹвͷȥ֫μ飬ڷھĿߣзаʲҲߣаУʷҲ硢ʪߺ϶ɱԣʪҲɢ֮ҩɿɾ÷Իʪȥ¼ƣͷ˷񣬲β߷󼲣ƺݴ󣬵ʳ֮ƷҲ

13.ݻԡ磬ɢ纮ʪ֮ҩҲ죬ǽʹ֫μLG֤˺̫ͷʹȣʹ޺˷ԣʸɣ򶻣δ͸÷ɢܷаëϳӸ׶֤ҲΪְ֮Ч֮ҩ಻ܶ书ܺУͷĿ֮磻ǼУϥ֮磻뵱Ѫ磻Ƣ磻աκ磻桢ȷ磻뾣γ磻顢ʹ磬з硢С磬羡ȥ֮ҩУɱѪҩ˿ɡ

14.磬ôƽɢ磬ƢθҩȻ֮ҩζᣬɢаһ֮ʹƷ3?ᡣʤ??ȥ?????ʵ???պ????Ψ??Ȼ˷ҩ??ɢϽ????÷??ˡ?5塷磬ͨһзаʡΪ١ͷʹ磬аĿäза֮ʢ֪ǽΪ֮ʹԣа֮ߣ֮Ϸҩ֮һָӡ¼вʹ֮Ҳв֣̫Ľͷȥһ䣬νߣǼָͷȥ֮авָ󣬱Ŀв֣ɶɾ֮Ҳ֫μǽ۱֤֮ߣ֮ʱҲھֱ֣һ²֮з缰˷֤зһѪڷɿ֮аԻھͨΣƺڷһԹ֮Ȼзһ֤޲аƣԲ󷢾ǹţǧ𡷡̨öܾƵȷԷΪʡ˶ߣΪˣڽ֮һ֤Ҫ֪߽Ѫ֮ηɿΪDZϢ磬Ϊؽ򲻿÷ҩ䱩塣¼ھ֣طǷ֮·ɢԡΪ粡֮ҩԷ֤Դһ书ã磬ͨϣЧ룬Ʒ㵱ζ֮޹Ҳ˵Ϊð纮跢ɢ֮ãδ̫֮dzΪй֮ϼȻߴɢɹѪ㣬ʼʵΪаˣδйסηԲڽʱ֮ߣʴʤ֮Ҳ䲻ڡ֮ңȻ֮ü֣ȷһ֮࣬аܣ񡢸ǼԵ֮磬Ѫ֮羷ֱϢ磬ΪΣɢͽ棬ֺ֮

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