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ҽҩȫ > ҩ > ҩ > J > ۹

۹

2017-05-24 21:19 Ķ:

йҩ䡷۹

ҩơ۹

ƴJú Gn

ӢRADIX PLATYCODONIS

ԴƷΪ۹ֲ۹Platycodon grandiflorumJacq.A.DC.ĸڣϴȥʰȥƤȥƤ

״ƷԲλԳʷĴΣ²ϸез֦Ť720cmֱ0.72cmɫ򵭻ưɫȥƤ߱ɫɫŤ幵к᳤Ƥߺۼ֧ۡϲкơеĶн϶̵ĸԣξۡʴ࣬治ƽ̹γɲ㻷ɫƤɫ϶ľưɫ޳ζ΢ࡣ

𡿣1Ʒ棺ľ˨ϸʱд棬ȥƤ˨Ƥ㣬ϸкС⾧Ƥխ϶ƤȺɢڣԺں΢ϸ״ɫγɲɻľʲܵɢڻۣʷ״Сϸǡ

2ȡƷƬϡװƬ΢¹۲죬ɼλԲεľǽᾧ

3ȡƷĩ1g7Ҵ-ˮ13Һ20mlȻ3Сʱ䣬ȷҡȡ2Σÿ20mlϲȷҺˮ30mlϴӣȥϴҺȷҺˮˮ˹ҺɣӼ״1mlʹܽ⣬ΪƷҺȡ۹ҩ1gͬƳɶҩҺձɫ׷¼ B飬ȡҺ10μlֱͬһ轺Gϣȷ-ѣ11Ϊչչȡɣ10ҴҺ105ߵɫƷɫУҩɫӦλϣͬɫİߵ㡣

ơȥʣϴ͸кƬ

ƷΪбԲλ򲻹ƬƤѳȥżвƤưɫխγɲ㻷ԣɫľн϶϶ʴ࣬ϡ[ⶨ]µķⶨղ5.5

ζࡢƽ

龭ξ

ΡΣʣ̵ŧڿ̵࣬ƲʹƣӸŧŧɲ

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ժ¼йҩ䡷

۹ͼƬ

ҩǵ䡷۹

ҩơ۹

ƴJú Gn

dҩ硢ݡ¬磨ձݡͼs¼๣Ϫķ۹Ŀҩֲҩ־

ԴΪ۹ֲ۹գʵϼѡȡȥҶϴˮУȥƤɹɡӦɡ

ԭ̬۹ҶˡɳͲˡɽ

ݱ3090ףȫ⻬ëʣԲΣзֱ֦һ֦ҶޱھС²Ҷ34ƬϲҶʱΪҶƬ״Σ36ף12.5ףȶ˼⣬ШλԲΣԵоݡھ״򣻻״ȶ5ѣ״ɫ35ף5ѣƬΣ5˿̣󣬻ҩΧƻܣӷλ5ңͷ5ѣë˷Σʱ5ѡΣ3⡣79¡810¡

ֲҰɽ²ݴСҹ󲿷ֵзֲȫؾաϡ֡ӱɹŵȵء

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ѧɷ֪֡߰ɷԶ־ᣬ۹߰Ԫǡֺ޴α-ݪ-β-D-߰Δ7-ϩ֬ǡ۹ǡִӽ۹õϩʣ۹ABC

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ҩá̵

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ڷ۹ˮƾȡʹѪ½ļ򲡣ѪǵøԭĽҩɻָ۹߰ܽʹڵ޴޴ûʳķڣԵ޴лӰ졣ˮ״ƤѢá

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ڡĿ"۹񵫹ȥƤˮһҹƬ΢á"

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١"΢¡"

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Ρ̵ŧпԣʺʹӸŧвʹʹ

١"вʹ絶̣ģּ"

ڡ¼"೦θѪȡԣȣƺʹ"

ۡҩۡ"Ѫȥ̵ۣѣ棬ʹжС"

ܡջӱݡ"һֹתĸʹͣа£̵֢Ѫŧ©ԡ"

ݡ塷"ηӸ"

ޡҡ"ʺʹα"

꽣"Σʺռʹ飬βȣͷĿϡ"

ࡶĿ"Ŀʹ"

ᡶҩԾ𷨡"顣"

÷ڷ12Ǯ衢ɢ

ע⡿ԡ漰Ѫ߼ɷ

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̵Դ۹һ롣ΪɢͯСȡĺϣȥ·Ҫڷ

κԼ۹ˮȡһٷ֮ǧ𷽣

κʵأ֤ߣ۹֣Ͷһ֣ȥƤģڣ֬ĸ֡ζΪɢ԰ͷǿ˰Ǯذ߼֮ϱ£±һֹһ˺ۡɢ

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ηͬϡ

ϳʹý۹޲ӣȷΪĩڷ

йDz۷磨ʹý۹ϸӣӴ󡣹ڣҧסþԿڡ

۾ʹ۷ڡý۹һǣţͷϸ۳裬Ӵÿʮ裬ˮ¡һΡ˷"۹"

ұѪֹý۹ϸˮȡÿһףһĴΡҩмϬţмɡ

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йѪѪ缦ɫųȺգý۹ϸÿһף¡һΡʱǿࡣԼ֮Ѫֹɳ塣ҩҲɼϬǣ۹ȷ֡

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١Ŀ"š顷Ʀʹý۹ǣȡͨҲپ˺ۡκʵأý۹ĸͶȡСȡƻҲηӸŧý۹ʲݣȡΣкŧѪ©Ҳ֤ʹý۹ʲݣȡɢƽȣ϶֮ܵҲʽͨʺڼӾ桢硢̣ʥҲùšҽԪ֮֡꣬ʧڭӣӰģӳƤԼ֪ĸĸȿʼζƶӸ˲ΣŻӰġŧѪңӰ׿ǣƦʵĿӡƣ׼ߣʹӻȣ߼ӷ硢棬߶ճӡƣ߼ӡ"

ڡݾ裩"۹Ӧƽ΢޶˺авʹ絶̣анģɢйʺͣа֤ͣӡּߣƢѪ㣬ִ֤ҩУ֮Ϊʤ֮ãʹְ֮Ҳ¼೦θѪߣָаอθԺͣѪҲȷԡСƺʹ¹ƶߣɢаⶾ֮ͨҲߣʹнݣƢʳӡȨȥߣɢа֮ҲջԳаӸŧϳβȣͷĿʹߣοͽ֮Ҳ"

ۡͨ"۹֮ãΩξΪ֮࣬ʹ½Ϊ֮Уʧӡ"

ܡݳԭ"۹֮вʹϽ֮رԣн֮½֮־ϣ£Уǽ۹Ϊ֮ҩ½ԿҲ"

ݡ桷"۹ҩУξ?Ե֮อͨһкаѪͨڷΣΪ̵մٱಫʹ򺮱ջĿʹöڷΣڴӸɿȣϽʹλ󳦣ʹܽԺڷΣϵ岻У򲻵½۹ϵ֮ҩΪҩ鮣֮ϸйֳ֮֮ɹȵԿ½֮˵ǡ"

ޡҩ"۹ŧҲʺʹ…پԻʹߣʲߣ۹Ҳ˸ʲߣ䶾֮ҲŧǸʲ֮䲻ߣ˼ӽ۹Ҳǹ֮ʹ۹ŧŧ"

ߡʡ"۹֮ᣬ֮ϽҩҲͨθʹνнӡȻϾҩϽʵ֤½޲ߣ̿Ҳ½׶ߣ֮䲡ϽԴ½ߣΪ֮˵ˡζ֮ҩϽ鮣Ѿ¡ζ֮ҩ½Уνʲ½ãϽΩаڷΡģߣʼ֮ʺ̵Ե֤Ω纮֮Ϊҩ֮彵ߣ಻Ҳ"

ժ¼ҩǵ䡷


лݡ۹

ҩơ۹

ƴJú Gn

ӢPlatycodon Root

dҩ硢ݡ¬㡢ͼ͡๣۹ҩ˸

ԡũݾ

1. պ뾰۹СҶ̣ʳ֮׷ôˣssܽҩν˲߱ǣǴ˽۹ҶƣsҶ¹ëΪ죬Ҷֲ˲߶

2.Ʊݡ˲̣Բ⣬ͷҶs˲Σӡs۹ҶߣҶĶߣһֱϣҶңΩԸ

ԴҩĻԴΪ۹ֲ۹ĸ

ֲﶯPlatycodon grandiflorus (Jacq.)A. DC. [Campanula grandiflora Jacq.]

պʹأ൱^ڣȥҶڳȫϴƬƬȥƤˮн2-3hɹɣȥ«Ƭɹɡ

ԭ̬۹ ݱ30-120cmȫаɫ֭ĴΣٷ֦ë֦ͨϲԷ֦Ҷ3-4Ƭޱм̵ıҶƬΣ2-7cm0.5-3cmȶ˼⣬ШΣԵмݣ汻׷ۡ1䵥򼯳״򣻻״Ƭ5״ֱ4-6cmɫɫƬ5Σ5˿ܱϸëӷλ5ѡԲΣʱ5ѡӶɫ7-9£8-10¡

ֲ̬ɽز¡Եࡣ

Դֲֲȫ

ࡿѧ ϲˬͺϲ⡣ں1100mµشɰУԸ׼طʵԼɳϺãΪ1꣬ڵأӳ0-418£䷢ѿʱȳ3.5-4ӷѿ70%¶18-25棬㹻¶ȣֺ15d硣

༼ ӷֱֳԷֱǰˮ24h0.3%ؽ12hﲥɣﲥΪáо20-25cm3-5cmǻңѹˮԼ2ڳ硣5cmңɼȥܻ磬10-15cm10cmඨ硣編ڽϸɺûйʱá150cm裬о5-10cm1-1.5cmʪԼ2ҳ硣γܵ磬ݣ4¼Դ

Ժ1ң5-10cmʱи׷1Σÿ1hm2ʩ嵭ˮ15000kg6-7¿ǰÿ1hm2ʩ150-225kg׷ʩҺ1ΡֲήʩʣӷΪڽ۹ڽϳĴӪժٶֵģ߸IJʢ1×10-3ϩ1ΣϴﵽĿġ龥ٺҪոԷ

Ʋ߿ݲΪҶ11100Һ50%1000Һڷڰγ꣬˾50%ʪԷۼ500Һע溦ؼףΪ۹90%аٳ800Һ50%п1000Һɱк֩롢ϻ桢ʳӳΪ

״״ ԲλĴΣ²ϸеķ֦6-20cmֱ1-2cm浭ưɫ΢йŤݹкƤۼ֧ۣʱɼδξĻɫɫ˨Ƥ϶˸«ͷ0.5-4cmֱԼ1cm߰εľۣ̽״Ӳ࣬۶ϣ۶Բƽ̹ɼ״϶Ƥɫγɲ㻷ɫľɫ΢ζ΢𡢿ࡣ

Ըʴ󡢰ɫʳʵζΪѡ

΢ 棺ľ˨ʱд棻ľǹϸżСƤ㴰Ƥ㣬ʱ϶Ƥ߽ɸȺȺɢУܱԺںɫ״γɲɻľʲܵɢڻۣʩ״Уľ߽ϿƷϸǡ

ĩ׻ɫپڶ࣬ˮȩҺװãϸеľſΡ֭Ϊн֭ܣֱ14-25μmںdzɫ͵μ״ơƼԵƿ׵ֱ16-72μmľϸ۳Σĩ˱΢״δȥƤĿɼľ˨ϸɫеĺϸСƽᾧ

ѧɷ֡߰ѷֵ18߰ǣ۹߰platycodinACD[1]D2D3ȥ۲ǻ۹߰deapioplatycodinDD32-O-=۹߰2-O-acetylplatycodinD23-O-۹߰3-O-acetylplaty-codinD2Զ־߰polyglalacinDD22-O-Զ־߰2-O-acetylpolygalacinDD23-O-Զ־߰3-O-acetylpolygalacinDD2۹߰-Amethyl platyconate-A2-O-׻۹߰-Amethyl-2-O-methyplatyconate-A۹߰-Aplatyconic acid-A lactone[2]ɷǽ۹߰D۹߰Aֽ2-O-۹߰D۹߰Cֽ3-O-۹߰Dֻ߰ȫˮ߰ԪУ۹߰Ԫplatycodigenin[3]Զ־ᣨpolygalacic acid[4]ԼĽ۹ᣨplatycodigenin[3]Զ־ᣨpolygalacic acid[4]ԼĽ۹ᣨplatycogenic acidABC[5]߰вˮ⣬õ8ִ߰pros-aponinڷԼλֵõģ3-O-β-D-ǻԶ־methyl 3-O-β-D-glucpyranosyl polygala-cate3-O-β-ǻԶ־methyl 3-O-β-laminaribiosyl polygalacate3-O-β-D-ǻ۹߰Ԫ3-O-β-D=glucopyranosyl platycodigenin methyl ester3-O-β-ǻ۹߰Ԫ3-O-β-gluctinobiosylplatycodi-genin methyl ester3-O-β-D-ǻ۹A3-O-β-D-glucopyranosyl platycogenin A lactone methyl ester,3-O-β-D-ǻ۹Adimethyl 3-O-β-D-glu-copyranosyl platycogenate A,2-O-׻-3-O-β-D-ǻ۹A dimethyl 2-O-methyl-3-O-methyl-3-O-D-glucopyranosyl platycogenate A[6].֬betulin,α-˲޴α-spinasterolα-޴-β-D-߰α-spinasteryl-β-D-gluco-side[2]

ҩá1.̵ãȮڷƷ1g/kgӺճҺķǿȿȻȡèԵ̵áб۹̵߰ǿԶ־Զ־Poygala senegaL.СӺ취Զ־۹߰ڷʱʺճĤθճĤij̶ֳȵĴ̼ճĤڿʹ̵Һϡͣʹųƽ۹߰áǻעȰЧΪ6.4mg/kg

2.Ѫãùθ۹ˮȡ200mg/kgʹѪ½ˮȡĽѪθ 25-50mg/kg׻Ƕơˮʹȡ500mg/kg4θʵнѪã͵ĸԭҩҲָʳѪȡýˮȡǿ

3.θҺںͿãƽ۹߰ڵ1/5ļʱƴθҺںͿá100mg/kgʱȫƴŽµθҺڡʮָע25mg/kgƽ۹߰ɷֹγɣƤעl0mg/kgƷ൱100mg/kg θ ӦγɵԤñƤע䰢Ʒ10mg/kgԴµģͣƽ۹߰ʹϵԼ٣ÿ25mg/kgЧȸʲȡFM100ÿ200mg/kgΪߡ

4.ãֽ۹߰пã1/10-1/5 ļԴ֫Dz˽Խ;пЧθС1/10 ļÿ1ΣҩԴѿҲãҶԴԹؽҲЧƼܽ͹ӦСëϸѪͨ͸ԡǻע۹߰СŤ巴Ӧ븹ǻθͬһ߰ɲơ۹ֱӿãˮȡǿϸɹܣǿ԰ϸɱܾøĻԡ

5.ѭϵͳãԴƽ۹߰ע䣬ɼʱѪѹ½ʼͺơĶŨʱʸԼáȮע200-800mg/kgֽ۹߰ܽ͹״֫ѪܵѪǿȿڼȡ4mg/kgע ʱҲӹ״ͺ֫ѪʱԵѪѹΪѪǶѪֱܵá

6.ãֽ۹߰򾲡ʹͽáСԷԻӳͱƵ˯ʱ䡣Եĵޱá۹߰ɽʹڵ̴ĺӵ̴͵йпͿ鰷ã鰷سθ۹2g/kg˫ྱɵijѪˮƺáƷ110״ƤѢãƷľ400mg/kgʱԴ߿Z56עϵͳSWA16бԵԡ

ԡ۹߰Ѫãע䣬ڷˮƻѪáСƤע䣬СΪ770mg/kg

Сθ۹İΪ24g/kgùθƷ40/kg24Сʱ5ȫΪ20/kgʱȫ۹߰кǿѪãѪָԴغޡɼʱ䡢ӹȶ죬1100 1 1000 ȣƤѪΪʲ 4.4-6.5ȥƤĽ۹ѪԴȥƤ۹˽۹עҩСƤעСΪ770mg/kgֽ۹߰θСʹİֱΪ420mg/kg800mg/kgƤעֱΪ22.3mg/kg14.1mg/kgθ۹߰ɷ˷Ż࣬ġŻ¡

ĩƬα-ŨҺɫ

ơʣȥ«ͷϴ̳͸Ƭɹɡ

1.׹ۡʹ۹ȥͷϼӲϸ֦ӣϸﱣðٺˮһʱáÿٺ֣Ͷˮн

2.Ŀ۹񵫹ȥƤˮһҹƬ΢á

ζζࣻƽ

龭Σθ

ΡΣ̵ʣŧ̵ࣻʺʹӸŧвʹʹС

÷ڷ3-10g衢ɢãջĩ

ע⡿ԡ漰Ѫ߼ɷ

1. ࣺ鼰ŭ߲ˡ

2.ԭԲãͨйҲ

ηӸȶʸɲʣʱȳþŧߣ۹һʲݶ϶ζˮȡһٷŧѪҲ(Ҫԡ۹)̵Դ۹һ롣ΪɢͯСȡĺϣȥ·(Ҫڷ)κԼ۹ˮȡһٷ֮(ǧ𷽡)κʵأ֤ߣ۹֣Ͷһ(ȥƤģڣ֬)ĸ֡ζΪɢ԰ͷǿ˰Ǯذ߼֮ϱ£±һֹһ(˺ۡɢ)˺Ʀ۹׿(ˣȥ)һ׶ˮһ룬룬ȥңֶ(׿)ã۹ȷ֡з֮(׼򷽡)

1.Ŀš顷Ʀʹý۹׿ǣȡͨҲپ˺ۡκʵأý۹ĸͶȡСȡƻҲηӸŧý۹ʲݣȡΣкŧѪ©Ҳ֤ʹý۹ʲݣȡɢƽȣ϶֮ܵҲʽͨʺڼӾ桢硢̣ʥҲùšҽԪ֮֡꣬ʧڭӣӰģӳƤԼ֪ĸĸȿʼζƶӸ˲ΣŻӰġŧѪңӰ׿ǣƦʵĿӡƣ׼ߣʹӻȣ߼ӷ硢棬߶ճӡƣ߼ӡ

2.ݾ衷۹Ӧƽ΢޶˺авʹ絶̣анģɢйʺͣа֤ͣӡּߣƢѪ㣬ִ֤ҩУ֮Ϊʤ֮ãʹְ֮Ҳ¼೦θѪߣָаอθԺͣѪҲȷԡСƺʹ¹ƶߣɢаⶾ֮ͨҲߣʹнݣƢʳӡȨȥߣɢа֮ҲջԳаӸŧϳβȣͷĿʹߣοͽ֮Ҳ

3.ͨ۹֮ãΩξΪ֮࣬ʹ½Ϊ֮Уʧӡ

4.ݳԭ۹֮вʹϽ֮رԣн֮½֮־ϣ£Уǽ۹Ϊ֮ҩ½ԿҲ

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6.ҩ۹ŧҲʺʹپԻʹߣʲߣ۹Ҳ˸ʲߣ䶾֮ҲŧǸʲ֮䲻ߣ˼ӽ۹Ҳǹ֮ʹ۹ŧŧ

7.ʡ۹֮ᣬ֮ϽҩҲͨθʹνнӡȻϾҩϽʵ֤½޲ߣ̿Ҳ½׶ߣ֮䲡ϽԴ½ߣΪҾ֮˵ˡζ֮ҩϽ鮣Ѿ¡ζ֮ҩ½Уνʲ½ãϽΩаڷΡģߣʼ֮ʺ̵Ե֤Ω纮֮Ϊҩ֮彵ߣ಻Ҳ

8.вʹ絶̣ģּ

9.¼೦θѪȡԣȣƺʹ

10ҩۡѪȥ̵ۣѣ棬ʹжСG

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12.塷ηӸ

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14. 꽣()ʺռʹ飬()βȣͷĿϡ

15.ĿĿʹ

16.ҩԾ𷨡顣

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