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ҽҩȫ > ҩ > ҩ > K > ľ

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2017-01-07 20:21 : Ķ:

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ƴK Mù

ӢRAMULUS ET FOLIUM PICRASMAE

ƤƤƤӡ൨ľϹľܵ

ԴƷΪľֲľPicrasma quassioides D. DonBenn. ĸ֦Ҷġգ

״Ʒ֦ԲΣ̲һֱ0.52cmɫɫϸܵƼ״Ƥףʴ࣬۶ϣ治ƽɫ֦ɫdz貿ϴҶΪ״Ҷ䣻СҶ״Բλ״Σޱ416cm1.56cmȶ⣬ƫбԲԵߴݣͨɫе±浭Ϻɫë΢ζࡣ

𡿣1ƷĩɫҶϱƤϸΣ±Ƥϸ࣬ײʽҶϸкڶƴؾάϸΧϸƴؾżγɾά

2ȡƷĩ1gӼ״10mlҹ˹ҺɣӼ״1ml ʹܽ⣬ΪƷҺȡľҩ1gͬƳɶҩҺձɫ׷¼ B飬ȡҺ10μl,ֱͬһȼ׻άΪϼĹ轺DZϣȷ£״17:3ΪչչȡɣԸ⻯ҺƷɫУҩɫӦλϣͬɫİߵ㡣

ơȥʣ֦ϴ͸ƬɹɣҶˮ˿ɹɡ

ζ࣬С

龭Ρ󳦾

Ρȣʪⶾڷȸðʺʹкʪܣҧˡ

÷֦34.5gҶ13g

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ժ¼йҩ䡷

 

ҩǵ䡷ľ

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ƴK Mù

ӢIndian Quassiawood Twing and Leaf

ӡƤ൨ľܵ

ԴΪľֲľPicrasma quassioides D.DonBenn.֦Ҷȫɲɣɹɡ

ԭ̬ҶľƤҺɫƽлɫƤ׼ƣС֦ɫɫҶ״ҶСҶ915λ״ԲΣ410cm24.5cmȶ⣬Ե߲۾ݣëɡ״״ҸꣻƬꡢPӷƤ45˹Σ34ɫࡣ46¡

ֲɽ¡ɽȼ߽ϳʪڻƺϸء

״֦ԲΣֱ0.52cmɫɫϸƼ״ƤףʴࣻľοƬ״ɫҶΪ״ҶСҶ״Բλ״Ρ΢ζࡣ

ѧɷ֡ľANnigakilactone ANCGpicrasin CGľȩCCľͪnigakinone׻ľͪ-Ǽ׻-β-֣-hydroxymethyl-β-carbolineȡ

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ΡʪⶾڸðԱססʪҧˡ

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ƴK Mù

鬰ɽܵܵ൨ѿڿࡢ̴ľƤӡ㵨㵨ľľ˪൨ľϹľ൯ӡ鬡ҰľӸӡ

ԴҩĻԴΪľֲľľġ

ֲﶯPicrasnia quassioidesD.DonBenn.Rhus ailanthoides BungePicrasma ailanthoides (Bunge) Planch.

պʹأȫɲɣȥƤϴƬɹɡ

ԭ̬ľ ҶľСľ7-10mƤҺɫ֦ɫëԵĻɫƤס״Ҷ֦ˣ20-30cmСҶ9-15״Σ4-10cm2-4cmȶ˽⣬ШΣ಻ԳƣԵ߲ݣɡҸܻ12cmܱëԣɫƬ4-5Σë4-5ΣƬԼ24-54-5ѵĻ̻ƻۻСӷΣ4-5ң4-5˴ӵŤתϡ˹Σʣɫ3-4޴滨ࡣ4-5£8-9¡

ֲ̬ں2400mµʪֵɽءԵϪߡ·Եȴ

Դֲֲڻƺϸء

״״ ԲΣִ30cmƬ1cmɫɫɢҰɫơĴĿƬɫƬԣ߷״СʼӲ۶ά״΢ζࡣ

΢𣺾棺Ϊľ˨ϸ˨ڲά2-20ɢڣϸеؾƤάгʲ״άڱľ۳140-240μmֱ12-20μmϸ⣻еؾؾֱ16-20μmľʲɵܡľάľϸɣľڳɫںľ1-5ϸߵƿס

ѧɷ֡1.ľ(kumujian)A1--(1-carboethoxy-carbo-line)ľB1--(1-carbomethoxy-carbo-line)ľC1--(1-formyl-carboline)ľD45-ʺͪ(45-dimethoxy-canthin-6-one)ľEʺͪ(canthin-6-one)ľF4-ʺͪ(4-methoxy-canthin-6-one)ľG1-ϩ-48--(1-vinyl-4, 8-dimethoxy-carboline)ľ(picrasidine)CDEɺľ(quassin)ľ(pi-crasmin)(picrasin)ABCDEFGľȩ(nigakihemiacetal)ABC, ľ(nigakilactone)ABCDEFGHIJKLM֦(24Z)-27-ǻ-3--724-ϩ-21-ȩ(24Z)-27-hydroxy-3-oxo-724-tirucalladien-21-al, (24Z)-27-ǻ-724-ϩ-3-ͪ(24z)-27-hydroxy-724-tirucalldien-3-oneݣ(24Z)-3 --3 --27-ǻ-724-ϩ-3-ͪ(24Z)-3 -oxo-3 -homo-27-hydroxy-7, 24-tirucalldien-3-oneݣ(24Z)-27-ǻ-3--724-ϩ-21-methyl(24Z)-27-hydroxy-3-oxo-724-tirucalladien-21-oateݣ(24Z)-724-ϩ-3β 27-(24Z)-724-tirucalladiene-3β27-diolݣ(24Z)-3β27-ǻ-724-ϩ-21-ȩ(24Z)-3β27-dihy-droxy-724-tirucalladien-21-alݡ1-ϩ-4, 9--(1-vinyl-4, 9-dimethoxy-carboline)-3-(48--)-1-ݼͪ -carbelin-1-yl-3-(48-dimethoxy-carbolin-1-yl)-1-methoxypropylketoneݣ1-һ-4--(1-ethyl-4-methoxy-carboline)5-ʺͪ(5-methoxy canthin-6-one)ʺͪ(canthin-6-one)1-ϩ-4-1-ϩ-48--, 1--ǰ1-Ǽ׻-(1-hydroxymethyl-carboline)1--ľͪ(nigakinone)׻ľͪ(methylnigakinone)3-׻ʺ-56-ͪ(3-meihyl-cantin-56-dione)ľ(kumujancine)H1--4--(1-formyl-4-methoxy-carboline)ľ(kumujanvine)I3-methyl 3( -carbolin-1-yl)propionateݣ1-ϩ-4--3-׻ʺ-26-ͪ(3-methyl-can-thin-26-dione)⣬п߰(picrasinoside)AB

ҩá1ѪӰ죺ľеʺͪþע0.3mg/kgóθѪʣʸΪ15%10%ľD5-ǻ-4-ʺͪ5-ǻ-ľFͿľBóѪʡԿľѪĻƵо֣ľеcAMPøáӿľ뵽1-̼-ţcAMPøãIC50Ϊ3.6 × l0-5 mol/L5-ǻ-4-ʺͪIC50Ϊ1.4 × l0-5molL, 45-ʺͪIC50Ϊ10.4 × l0-5

2ãӿľз뵽Ŀ߰-Bܰϸ԰ѪP388ϸãǿ5-ड

3ãľе -пĻԡľ֦ҶƳɵעҺ2gҩmlС0.2-0.5mlֻȮ8mlֻƤע䣬߶жС͹зdzŵıãС󱣻Ϊ75.6%Ϊ100%

ȡƷַ2gҴȡȥҴ󣬼ˮܽ⣬ȷȡɣˮ2mlܽ⡣ȡ1mlҺ¹۲죬ɫӫ⣬μҺԵɫӫ⡣2ȡҺ1mlҺ2-3ΣҺϺɫɫ ȡƷĩ1gӼ״10mlҹ˹ҺáԿľBCDFΪƷڹ轺GϣȷΪչչ18cmԸDra-gendorff-Wagner11ԼΪɫɫƣ365nm¹۲죬ƷƷӦλôͬɫӫߵ㡣

ζࣻС

ΡȽⶾʪɱ档ϺȾףθףȾܣѢʪˮˣҧ

÷ڷ6-15g30g衢ɢãˮϴĩ󣻻Ʋ롣

ע⡿Ʒһԣڷ˹и

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