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ҽҩȫ > ҩ > ҩ > Q > Ǽ

Ǽ

2017-05-16 23:43 Ķ:

йҩ䡷Ǽ

ҩơǼ

ƴQin Huó

ӢRHIZOMA ET RADIX NOTOPTERYGII

ǼǼͷǼӻҩ

ԴƷΪɡοֲǼۣNotopterygium incisum Ting ex H. T. Chang ҶǼNotopterygium forbesii Boiss. ĸڣȥɳɹɡ

״ǼΪԲ״ĸ413cm,ֱ0.62.5cm˾߾ۡغɫںɫƤ䴦ʻɫڼ̣ʽ¡Ļ״Ʋϰ“Ǽ”ڼӳ״ϰ“Ǽ”ж״״ͻĸۼɫƬᣬʴ࣬۶ϡ治ƽж϶Ƥɫɫɫ͵㣬ľưɫԣ貿ɫɫ㣬ζ΢

ҶǼΪԲΣ˾߾ҶʲлԲ׶ΣƼƤףغɫнܵĻƣ815cm,ֱ13cmϰ“Ǽ”еĸִ󣬲״ϸϰ“ͷǼ”ɴ࣬۶ϡƽ̹Ƥdzɫľưɫζϵ

ⶨջӷͲⶨ¼ DⶨƷӷͲ2.8ml/g

ơȥʣϴ͸кƬɹɡ

ζ࣬¡

龭ס

Ρɢ磬ʪֹʹڷ纮ðͷʹʪʹ米ʹ

÷39g

ءﴦ

ע1ͬţβHeraeleumֲĸǼá

2Ǽܷɢ纮ֹʹڸð纮ͷʹʹΪ硢ƵҩͬáǼʪҲΪţΪʤʪ֮ƷһΪƷԷʪʹΪˣʹ硢ͬáͷʹ֢ϴܺϸӦá

3ΪҩʱӦֹʹЧнٴڷ纮֢ʱͷʹǽʹ֢ſʹáηʪʹޱ֢ӦáݽٴʵᣬƷȵĹЧܺãҩѹӢƷηȱ֢һ֮ٶȷ󡣵ƷζŨң࣬Ż£ʹʱע⻼ߵθʵ

ժ¼йҩ䡷

ǼͼƬ

ҩǵ䡷Ǽ

ҩơǼ

ƴQin Huó

ǼࡢǼʹߣʹߣձݡǼܡ˷ʹߣҩҩѧҩຣҩġ

ԴΪɡοֲǼҶǼǼȡȥҶϸɹɻɡ

ԭ̬Ǽ

ݱߴ1ϡ״Բ״ֱ浭ɫݹƣпգëҶ²ҶΪ23ص״ҶҶ1020ף״СҶ34ԣ״ΣСҶƬ2״ѣƬ߲ȵĶ۾ݣһСҶ߱һԸҶޱϲҶޱʳεʶҶƬɫ浭ɫëɡλҸɡ1015ö̲ȣֲڣܰСɡλԼл2030䣻Ƭ5öƬΣɫ5öΣȶ˼⣬۾5˿ϸҩԲΣ2ң2ö̶ۣѹ״Բ׶ΣӷԲΣλ2ҡ˫ԲΣƽë⼰гᣬ޳ᣬۼͨ͹34͹56ʵʱѿ2ֹĶˡ89¡910¡

ڸɽľֻݴСֲຣĴϡࡣ

ڿҶǼǼ

ݱ80100סиϺɫݹƣëпգ²Ҷ2ػ3ص״ҶҶ79ף״СҶƬ״Σ24ף12ףȶ˽⣬Ե״ѣϲҶƬ𽥼򻯶ɹɫҶʣëҶëɡλСɡ1ףСܰƬΣСɡȳԶ̣5ƬΣ5Ƭɫ״Σ2ף0.6ףȴ⣬۾5ö뻨껥ҩԲΣ˿ӷλ2ң2̡˫6ᣬı֦Угᣬ֦޳ᡣӺڰ78¡

Ұڸɽɽ²ݴԼľСֲĴຣϵȵء

۴Ǽ

ݱ60100סִ󣬽ڼ伫̡ɫݹơ²ҶΪ32״ҶԼ30ףʱɴ60ףҶԼΪȫ֮룬ϸ⣬״СҶѣ²һСҶбೣޱƬλΣԵм۵ĴֳݣëɡλҸɡ1520ö֦ƽܰСܰΣ55ɫΣȶھ5͹ͷ2˫Σгᣬ޳ᣬ3478¡

ֲĴȵء

״Ǽҩҩòֺ̬ͬвǼǼͷǼǼ֡

ٲǼ˿ǼΪĸ̬ƲϡԲ״Լ410ףֱԼ12סоҶлغɫжܶ¡Ļڡ״ͻۡ۶ϣ治룬ԵľջƺͶ϶Ƥغɫľʲɫлưɫ裬ɰ㣨͹ܣζ΢顣

ǼĻڽϡ״ƲǼԴ

۴ͷǼĻر󣬳ʲſ״Сȣ˾߶Ǽͬ

ǼΪĸ֧Բλ֦317ףֱԼ0.71.7ףżɼиغɫƼ״ͻۣ϶˽ϴִϡ¡Ļڣɶࡢ۶ϣ治ƽ̹Ƥdzɫľưɫоջƣɰ㲻ԣ衣ζϵ

Ͼ׳¡ۻơʽܡɰࡢŨΪѡһΪǼƷţǼ֮ͷǼΡ

ĴƴǼࡢຣǼ⣬ϡ½صȵ

ѧɷ֡ҶǼӷ͵ȡ

ơȥʣϴ͸Ƭɡ

ζ࣬¡

١ҩۡ"ζ޶"

ڡҽѧԴ"Ҫƣ£ζ"

ۡҺݡ"΢£ζʣƽ"

龭ס

١ҡ"̫׾""̫С"

ڡҺݡ"̫"

ۡܡ"̫֡"

Ρɢʪؽڡθð纮ͷʹ޺纮ʪԣǿǽۣˮףӸҴ

žƵϥʹйкΰ磬ͺɢʤʪֹʹ

1з纮񺮷ȣͷʹʹ֤Ʒнǿķɢ纮ֹʹЧ硢ơϸͬãζǼ

2ڷ纮ʪаϮµ֫ʹ米ʹϰʹΪáƷʤ£ɢֹʹ硢ͬãñ

١ҩۡ"硢ʧѪ񮣬㲻죬аԡ"

ڡջӱݡ"һз粢ȭΣ֫ӣͷĿۼˮˣǽۣͨࡣ"

ۡҡ"̫ͷʹȥǽʹµ"

ܡƷ㾫Ҫ"ٽʹ˷а¾ɷʪŸҴ."

ݡݱҪ"кѸη磬ηʪಫ̫ͷʹΪǿʣվᾷз粻ͷĿࡣ"

ޡԼҽ"а׳޺"

÷ڷ25Ǯ衢ɢ

ע⡿Ѫʹɷ

ݾ衷"Ѫͷʹʹʹߣ֤÷硣"

ءøﴦ

θðȣףǼǮѹӢһˮ壬ÿһֶηϺҽѧԺҽԺ

̫˺޺Ǽ桢硢ƤʲݡҽǼ

۽ٺǼ硢ϸܺơءˡʲݡˮȷԸͶ֮·Ͷ֮ԪؾζǼ

̫ͷʹ֣Ǽ֣춹Ϊĩڴ֮΢塷

οͺԣʹݣ䣬ڱ֤֮ǼһǮӡɽ֣˸ʲݰ˷֡ˮҽѧǼ

ηʪಫ۷ʹ죬΢ײʣǼȥ«ӣڣȥƤ꣩ʲݣˣȷ֡ÿǮˮһյ롢Ƭ߷֣ȥң·ʱ򡣣Ǽ

μ米ʹɻعˣʹǿۣưߣǼһǮ޻硢ʲݣˣ֣ܺ֡һˮյһյȥ·ʳǰ˱桷Ǽʤʪ

١Ʊݡ"ƷöˮǼ"

ڡҽѧԴ"Ǽ֫ʹ̫ҩҲӴ̫ܺͷʹ͸ڣηʪؾƣ壺̫һҲʪ棬Ҳȥ֫ʹҲӸҰѪҲηʪͷʹҲ"

ۡݻԡ"Ǽ֫壬ͨѪаɢ纮ʪ֤֮ŧжĿ֤֮ɬʹѿ֤档أǣζɢжֹͷ㣬֫壬֮аҲ"

ܡԭ"Ǽȴҷ֮˧……ʤʪǼˮʪܺ˕ͬã̫ͷʹɢ͸ڣʱð֮ҩҲкڲ֮òԢк֮⡣"

ݡ塷"ǼŽԲ֣νһǼԡ¼ֹжǼϡĿɡȻɫ죬ζŨ֮⣬ʤ赼ѪΪáͨأ磬书һǼ֮ʤֱ϶ۣ֧ۣԾѷְֹ֮ͨͨظϥ֮ʦţǼרϲ֮纮ʪа֮ר߽Ȼã书Ƚݣ֮һзʪаڼֱϣ£ǼΪΡ֮֫ǣΣ½ʹ򾹺϶֮ͨӦ̲ڿűԣӦЧ֮纮ʪаĪͶ顣ְǼ֮ʣڷ纮ʪʪȣʪаȣΪ²֮ȻΩڿ֤ΪȻ֮ʪߣǽڽǼ֮ͨΪΣЧػȲ಻ãΪ򵼶ʹְ֮ᣬ֮ҩʪ֮෢Զּ֮DZнȻΪҲ"

ժ¼ҩǵ䡷


лݡǼ

ҩơǼ

ƴQin Huó

ӢIncised Notopterygium ,Incised Notopterygium Rhizome Forbes Notopterygium Rizome, Rhizome or root of Incised Notopterygium, Rhizome or root of Forbes Notopterygium

ǼࡢǼʹߡʹߡǼ˷ʹߡҩ

ԡũݾ

ԴҩĻԴΪɡοֲǼҶǼĸ͸

ֲﶯ1.Notopterygium incisum Ting ex H. T. Chang2.Notopterygium forbesii de Boiss.(N. fran- chetii de Boiss)

պʹأ3-4^紺ѿǰϲ֣ȡɳȥ«ͷг10-13cmĶ̽ڣɹɻɡ

ԭ̬1ݱ60-150cm׳Բλ򲻹״ɫغɫпήҶʣֱԲΣпգ浭ɫֱϸơҶ²ҶгҶɻչĤҶʣҶƬΪ״ҶСҶ3-4ԣĩƬ״ԲΣ2-5cm0.5-2cmԵȱ״dzѣϲҶ򻯳״ޱȶ״ѵСҶƬɡλҸֱ3-13cm߳ܰƬ3-6Σ䣻ɡ7-18-392-10cmСɡλֱ1-2cmСܰƬ6=10Σ3-5mm״Σ5ɫΣȶ˶۶ڰĻ˿䣬ɫ2̣ܶƽѹ¡𡣷ֹԲΣ4-6mmԼ3mmչΪԼ1mmijᣬ͹ԣÿ3-45-6鸹ڰɹ״7-9£8-10¡

2Ǽڣֲ80-180cmҶƬ״ҶĩƬԲ״״Σ3-8cm1-3cmȶ˶ۻ򽥼⣬ԴШΣԵд־ݣϼҶԵ΢ëϲҶҶƬ򻯣3СҶɡλɡ10-17-23국ɫԲΣԼ5mm4mmÿ͹3-4͹47-8£8-9¡

ֲ̬ں2000-4200mԵ¡ȲݴСں1700-4500mԵڡ

ԴֲֲࡢຣĴصȵءֲɹšɽġࡢຣĴȵء

ࡿѧ ϲˬʪͺɡˮáֳʵɰ࣬ڵʪ֡

༼ ӻֳӷֳ^ճӣɹɣڴǶֱо33cmѨ23-27cmѨ5-7cmÿѨ10ǶѷʻֳԼ1-2cmˮÿ1hm215kgҡֳ^򴺼ʱУѡѿĸгСΣ1-2ѿԣо33cm15-17cm15cmѸŹڣÿ8-10cm1Σӷʻϸ14-16cmˮ

ֱ8-10cmʱ硢磬ÿѨ2-3ꡣÿи3Σ׷ʡԽʩǷʡѷʡӷʡƵȡøֳģ繤⣬ֱͬ

溦 棬ļ1110̲ʯˮΡ

״״ 1Ǽ ΪԲĸ4-13cmֱ0.6-2.5cm˾߾ۡغɫںɫƤ䴦ʻɫڼ̣ʽ¡Ļ״ƲϣϰƲǼӳ״ϰǼж״״ͻĸɫƬᣬʴ࣬۶ϡ治ƽж϶Ƥɫɫɫ͵㣬ľưɫԣ貿ɫɫ㣬ζ΢

2ҶǼ ԲΣ˾߾ҶʲлԲ׶ΣƼƤףغɫнܵĻƣ8-15cmֱ1-3cmϰǼеĸִ󣬲״ϸϰƴͷǼɴ࣬۶ϡƽ̹Ƥdzɫľưɫζϵ

Ը׳кΣɫʽܣɰ࣬ŨΪѡ

΢ 棬1Ǽľ˨Ϊ10ϸƤưƤƱƤ϶γɲɻľʲܽ϶ࡣƤожڵԲλ򲻹ԲΣֱ200μmں״

2ҶǼ Ǽͬ٣гƬľάȺ貿󡣷ڵֱ180μmĩػɫٷڵݶϸڱԺеɫPܻĺۼнɫ״ڱϸݳΣɫ͵ΡơԵҲֱ13-15μmľ˨ϸڳԻɫ

ѧɷ֡1.Ǽ 㶹໯ŷǰisoimperatorin0.38%8-ŷǰcnidilin0.5-ǻأnotopterol1.2%)bergapten0.009%)8-33-׻ϩ-5ȥ׻demethylfuroinnarin)5-ǻ-8-33-׻ϩ-֬[5-hydroxy-8(33-dimethylally)-psoralen0.012%]5-ȥ׻̴bergaptol0.088%ϻǰ߰Ԫnodakenetin0.04%)ϻǰ߰nodakenin̴-O-β-D-ǣbergaptol-O-β-D-glucopyranoside0.075%)6-O--κϻǰ߰6-O-trans-feruloylnodakenin0.022%)[1]ɽ۴colrmbianetin)ɽ۴߰columbiananine)ŷǰimperatorin)ӡȘXKأmarmesin)[2]Ի-ǻһp-hydroxyphenethyl anisate0.005%κᣨferulic acid0.89%)޴໯β-޴߰β-sitosterol glucoside)[1]β-޴β-sitosterol)[2]ӷͣԼ2.7%ɷα-ϩα-thujene)αβ-ϩαβ-pinene)βϩβ-ocimene)γ-ϩγ-terpinene)ϩlimonene)4-ϩ4-terpinenol)bornylacetate)α-ţͣϩαcopaene)ʽ-β-ϻϩβ-farnesene)ŷԣapiol)´guaiol)benzylbenzoate)[3]ࣺ֬ʮ̼methyltetradecanoate)12-׻ʮ̼12-methyltetradecanoic acid methyl ester)ʮ̼methylhex-adecanoate)4812-׻ʮ̼4812-trimethyl-tridecanoic acid methyl ester)14-׻ʮ̼14-methyl-hexadecanoic acid methyl ester)methyl-9-octadecenoate)Ӳ֬methyloctadecanoate)ʮ̼methyleicosanoate)11-ʮ̼ϩmethyl-11-eicosenoate)14֣ࣺ춬ᣨaspartic acid)Ȱᣨglutamic acid)ְarginine)ᣨleucine)ᣨisoleucine)Ӱᣨvaline)հᣨthreonine)ᣨphenylalanine)ᣨmethyionine)19֣࣬ǣrhamnose)ǣfructose)ǣglucose)ǣsucrose)[4]Ǽһκphenethylferulate)[5].2.ҶǼ ²ֺ㶹໯أberg-amottin,bergaptin),ŷǰ0.62%8-ŷǰ0.024%5-Ȼأ0.083%0.008%8-33-׻ϩ-5-ȥ0.03%̴0.026%ϻǰ߰Ԫ0.053%ϻǰ߰1.2%6-O--κϻǰ߰0.73)%[1],ɽ۴[5]Ի-ǻ׻ᣨ0.07%κᣨ0.83%)β-޴߰[1]ӷͣӷҪɷΪα-ϩ3630%β-ϩ21.04%)ϩ14.42%)⣬ȩhexanal)ȩheptanal)ȩoctanal)ϩsabinene)ϩcamphene)¹ϩmyrcene)α-ˮϩα-phellandrene)3-ϩ3-carene)2-ϩ2-carene)-ɡأp-cymene)αγ-ϩ4-ϩβ-ϩβ-selinene)20[6]

ҩá1.ȡã

1.1.ԽĸԴµӰ죺Ƥעl5%ĸҺ10ml/kgȺ2.5hȻֱǼӷ1.328mlkgθ0.133ml/kgθҩҩͬʱ¡ձȽֲͬ;ͲͬĻӷ;ʹԽͣŵĽá

1.2.Сױˮ׵Ӱ죺СֱθǼӷ1.3280.6640.3320.221mlkgҩҶζױ0.03mlֻҶƬmg飨12.5±6.01ȽϣֱΪ6.6±4.407.2±3.167.0±4.2115.9±5.28ǰ3ȽP0.05ƶױˮס

1.3.ԽDz˽͵Ӱ:ڷ1.3280.664mlkgǻע0.1330.066mlkgԴDzˣ1%0.1mláȽϿڷ1.328mlkgעDz˽34СʱP0.05ڷ0.664mlkg24СʱʱP0.001ǻע0.133mlkg24СʱP0.05

1.4.Դ͵Ӱ죺ڷǼӷ1.3280.6640.332ml/kgҩ30ڴĤע1.2%0.1mlֻȽϣ1.328mlkg飬356СʱʱŲP0.05

2.ʹãСڷl.328mlkgǻע0.133mikgǼӷ3죬Ըǻע0.5%Һ0.2ml/kgl0ӵŤԵļ١ȽмãPֵΪ0.001Сȴ̼ʹֵӳŵʹá

3.24ȱDNCBСٷӦӰ죺СθǼӷ1.328mlkgǻע0.133mlkg10죬DNCB³ٷͳӦһãȽͶȷֱΪ2.3±1.961.2±0.761.1±0.85

4.ʧãǼˮָܲСֱ1.5361012g/kgβעͷ0.06mgkgµʧŵĶԿãȽ36gkgPֵΪ0.0110gkgP0.00112gkgʱ÷½P0.05ڷ10gkgǼˮ֣ܲԾע0.04mgkgͷշʧʱƳмãȽP0.001ʧʱҲмẉ̂P0.001ÿڷǼˮܲ5g/kgȷ-ļʧijʱ䡣ǼڷۻһС󣬶ͷշʧijʱͳʱáҶǼˮСڷl0gkgӳʧDZں̳ʱ䡣ڷ20gkgʱֻСʧijʱP0.01Ǽˮ20gkgڷ󣬿ӳȻշҲʱ䣬P0.01

5.ԼļȱѪļӪѪӰ죺ǼӷͿڷڴȻβעԴҶ0.75ukgļȱѪ6%Ǽӷ0.6gkg3%Ǽӷ0.3gkgжԿļȱѪãȽPֱֵΪ0.01ͣ0.05ļ86Rbȡʣ۲ǼӷͶļӪѪӰ졣2.5%Ǽӷ0.75gkgļ86RbȡʣȽΪ21.1%P0.01

ԡǼӷ͹θСLD50Ϊ2.83g/kg6.64±0.8726ml/kgСԲͬǼӷ͹θ۲7죬LD50Ϊ6.64±0.8726mlkgǼˮܲŨȺθС12gkg۲72СʱСǼӷ0.75gkgθС󣬹۲24Сʱκ쳣ӦСθҩLD50Ϊ2.83gkg

1ȡĩ0.5g1h˹ҺŨ1ml7%ǰ״Һ2-3Ρ20%ҴҺ3Σˮԡ΢ȣȣȴ󣬼ϡpH3-4ټ1%ȻҴҺ1-2ΣѲ洦Ϻɫ㶹غࣩ

ơȥʣϴ͸Ƭɡ

ζζࣻ

龭ף

Ρɢʪؽڣֹʹз纮ͷʹ޺ӡʪԣˮף׶

÷ڷ3-10g衢ɢ

ע⡿1.Ѫʹɷ

2.ݾ衷Ѫͷʹʹʹߣ֤÷硣

1.ƱݡƷöˮǼ

2.ҽѧԴǼ֫ʹ̫ҩҲӴ̫ܺͷʹ͸ڣηʪؾƣ壺̫һҲʪ棬Ҳȥ֫ʹҲӸҰѪҲηʪͷʹҲ

3.ݸĿǼ󡢶ʤʪ͸ڣиӲͬ

4.׹ҩԽ⡷Ǽ֣ܳ۶ɢɷа̫С̫η磬书ͬʵ

5.ݻԡǼ֫壬ͨѪаɢ纮ʪ֤֮ŧжĿ֤֮ɬʹѿ֤֮档أǣζɢжֹͷ㣬֫壬֮аҲ

6.ԭǼȴҷ֮˧ʤʪǼˮʪܺͬã̫ͷʹɢ͸ڣʱð֮ҩҲкڲ֮òԢк֮⡣

7.塷ǼŽԲ֣νһǼԡ¼ֹжǼϡĿɡȻɫ죬ζŨ֮⣬ʤ赼ѪΪáͨأ磬书һǼʤֱ϶ۣ֧ۣԾѷְֹ֮ͨͨظϥ֮ʦţǼרϲ֮纮ʪа֮ר߽Ȼã书Ƚݣ֮һзʪаڼֱϣ£ǼΪΡ֮֫ǣΣ½ʹ򾹺϶֮ͨӦ̲ڿűԣӦЧ֮纮ʪаĪͶ顣ְǼ֮ʣڷ纮ʪʪȣʪаȣΪ²֮ȻΩڿ֤ΪȻ֮ʪߣǽڽǼ֮ͨΪΣЧػȲ಻ãΪ򵼶ʹְ֮ᣬ֮ҩʪ֮෢Զּ֮DZнȻΪҲ

8.ҩۡ硢ʧѪ񮣬㲻죬аԡ

9.ջӱݡһз粢ȭΣ֫ӮӣͷĿۼˮˣǽۣͨࡣ

10.ҡ̫ͷʹȥǽʹµ

11.Ʒ㾫Ҫٽʹ˷а¾ɷʪŸҴ

12.ݱҪкַ磬ηʪಫ̫ͷʹΪǿʣվᾷз粻ͷĿࡣ

13.Լҽа׳޺

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